Prognostic factors are associated with the risk of future health outcomes in individuals with a
particular health condition or some clinical start point (eg, a particular diagnosis). Research …

Background Intermediate hyperglycaemia (IH) is characterised by one or more
measurements of elevated blood glucose concentrations, such as impaired fasting glucose …

Importance Echocardiographic left ventricular global longitudinal strain (GLS) detects early
subclinical ventricular dysfunction and can be used in patients receiving potentially …

Organisations such as the National Institute for Health and Care Excellence require the
synthesis of evidence from existing studies to inform their decisions—for example, about the …

Background In meta-analyses of diagnostic test accuracy, routinely only one pair of
sensitivity and specificity per study is used. However, for tests based on a biomarker or a …

Objectives: This systematic review aimed to identify and evaluate prognostic factors for long-
term (≥ 6 mo) physical functioning in patients with chronic musculoskeletal pain following …

Rationale & Objective Coronavirus disease 2019 (COVID-19) disproportionately affects
people with chronic diseases such as chronic kidney disease (CKD). We assessed the …

Background The clinical significance of cardiac troponin measurement in patients
hospitalised for coronavirus disease 2019 (covid-19) is uncertain. We investigated the …

Objective To assess the role of sex as an independent prognostic factor for mortality in
patients with sepsis admitted to intensive care units (ICUs). Design Systematic review and …

Background/Objective: Sex-related differences among patients with aneurysmal
subarachnoid hemorrhage (aSAH) and their potential clinical implications have been …