Non-coding RNAs and their integrated networks

P Zhang, W Wu, Q Chen, M Chen - Journal of integrative …, 2019 - degruyter.com
Eukaryotic genomes are pervasively transcribed. Besides protein-coding RNAs, there are
different types of non-coding RNAs that modulate complex molecular and cellular …

Emerging role of non‐coding RNA in health and disease

GK Bhatti, N Khullar, IS Sidhu, US Navik… - Metabolic brain …, 2021 - Springer
Human diseases have always been a significant turf of concern since the origin of mankind.
It is cardinal to know the cause, treatment, and cure for every disease condition. With the …

LncRNA-MIAT promotes thyroid cancer progression and function as ceRNA to target EZH2 by sponging miR-150-5p

K Guo, K Qian, Y Shi, T Sun, Z Wang - Cell death & disease, 2021 - nature.com
While long noncoding RNAs (lncRNAs) have been reported to play an important role in
human cancer types, they remain poorly understood in papillary thyroid carcinoma (PTC) …

[HTML][HTML] Comprehensive characterization of lncRNA-mRNA related ceRNA network across 12 major cancers

Y Zhang, Y Xu, LI Feng, F Li, Z Sun, T Wu, X Shi, J Li… - Oncotarget, 2016 - ncbi.nlm.nih.gov
Recent studies indicate that long noncoding RNAs (lncRNAs) can act as competing
endogenous RNAs (ceRNAs) to indirectly regulate mRNAs through shared microRNAs …

Constructing prediction models from expression profiles for large scale lncRNA–miRNA interaction profiling

YA Huang, KCC Chan, ZH You - Bioinformatics, 2018 - academic.oup.com
Motivation The interaction of miRNA and lncRNA is known to be important for gene
regulations. However, not many computational approaches have been developed to …

[HTML][HTML] Construction of differential mRNA-lncRNA crosstalk networks based on ceRNA hypothesis uncover key roles of lncRNAs implicated in esophageal squamous …

S Yang, Q Ning, G Zhang, H Sun, Z Wang, Y Li - Oncotarget, 2016 - ncbi.nlm.nih.gov
Increasing evidence has indicated that lncRNAs acting as competing endogenous RNAs
(ceRNAs) play crucial roles in tumorigenesis, metastasis and diagnosis of cancer. However …

LncRNAs and PTEN/PI3K signaling: A symphony of regulation in cancer biology

WH Almalki - Pathology-Research and Practice, 2023 - Elsevier
Abstract The Emergence of Long Non-coding RNAs (lncRNAs) as Key Regulators in Diverse
Biological Processes: A Paradigm Shift in Understanding Gene Expression and its Impact on …

[HTML][HTML] LncRNA GAS5 contributes to lymphatic metastasis in colorectal cancer

Y Zheng, D Song, K Xiao, C Yang, Y Ding, W Deng… - Oncotarget, 2016 - ncbi.nlm.nih.gov
Colorectal cancer (CRC) ranks the third most common type of cancer worldwide. However,
the detailed molecular mechanisms underlying these processes are poorly understood …

LINC00467 promotes cell proliferation and metastasis by binding with IGF2BP3 to enhance the mRNA stability of TRAF5 in hepatocellular carcinoma

W Jiang, X Cheng, T Wang, X Song… - The journal of gene …, 2020 - Wiley Online Library
Background Hepatocellular carcinoma (HCC) has been recognized as a member of the
most common human malignant tumors globally. According to multiple studies, long …

Surveying lncRNA-lncRNA cooperations reveals dominant effect on tumor immunity cross cancers

T Shao, Y Xie, J Shi, C Yang, H Zou, Y Li, J Xu… - Communications …, 2022 - nature.com
Long non-coding RNAs (lncRNAs) can crosstalk with each other by post-transcriptionally co-
regulating genes involved in the same or similar functions; however, the regulatory …