The X chromosome is a key player in germ cell development, as has been highlighted for
males in previous studies revealing that the mammalian X chromosome is enriched in genes …

Genome instability may play a role in severe cases of male infertility, with disrupted
spermatogenesis being just one manifestation of decreased general health and increased …

CAG trinucleotide repeats in androgen receptor (AR) gene encode a polyglutamine tract in
AR N-terminal transactivation domain. Studies have been conducted to evaluate the effect of …

Male infertility is a multi-factorial and multi-genetic disorder, and the prevalence of male
infertility in the world is estimated at 5–35%. The search for the causes of male infertility …

Androgenetic Alopecia (AGA) is by far the most common cause of hair loss in men, and its
high prevalence has been reported in detail for many decades [1]. Several different terms in …

Testicular germ cell tumors (TGCTs) represent the most common solid tumors affecting
young men. They constitute a distinct entity because of their embryonic origin and their …

The question about genetic causes of a global decrease in male fertility observed in recent
decades in many countries is among the hot spots of reproductive genetics. An impairment …

The incidence rate of prostate cancer (PCa) has risen by 3% per year from 2014 through
2019 in the United States. An estimated 34,700 people will die from PCa in 2023 …

Premature ejaculation is one of the most common sexual disorders in men due to
uncontrolled modulation of spinal reflexes controlled by cortico‐limbic centers in the brain. In …

Background. Chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) refers to a
common disorder with unclear etiology and unsatisfactory treatment, which reduces the …