Drug self-delivery systems for cancer therapy

SY Qin, AQ Zhang, SX Cheng, L Rong, XZ Zhang - Biomaterials, 2017 - Elsevier
Carrier-assistant drug delivery systems (DDSs) have been rapidly established for cancer
therapy and great strides have been made in recent years. However, further development of …

Aptamer-based biosensors for biomedical diagnostics

W Zhou, PJJ Huang, J Ding, J Liu - Analyst, 2014 - pubs.rsc.org
Aptamers are single-stranded nucleic acids that selectively bind to target molecules. Most
aptamers are obtained through a combinatorial biology technique called SELEX. Since …

Nucleic acid and peptide aptamers: fundamentals and bioanalytical aspects

M Mascini, I Palchetti, S Tombelli - … Chemie International Edition, 2012 - Wiley Online Library
In recent years new nucleic acid and protein‐based combinatorial molecules have attracted
the attention of researchers working in various areas of science, ranging from medicine to …

Current and prospective protein biomarkers of lung cancer

TN Zamay, GS Zamay, OS Kolovskaya, RA Zukov… - Cancers, 2017 - mdpi.com
Lung cancer is a malignant lung tumor with various histological variants that arise from
different cell types, such as bronchial epithelium, bronchioles, alveoli, or bronchial mucous …

Aptamers in analytics

M Ilgu, M Nilsen-Hamilton - Analyst, 2016 - pubs.rsc.org
Nucleic acid aptamers are promising alternatives to antibodies in analytics. They are
generally obtained through an iterative SELEX protocol that enriches a population of …

Prodrugs: a challenge for the drug development

JB Zawilska, J Wojcieszak, AB Olejniczak - Pharmacological reports, 2013 - Springer
It is estimated that about 10% of the drugs approved worldwide can be classified as
prodrugs. Prodrugs, which have no or poor biological activity, are chemically modified …

Investigation of ellagic acid rich-berry extracts directed silver nanoparticles synthesis and their antimicrobial properties with potential mechanisms towards …

S Ekrikaya, E Yilmaz, C Celik, S Demirbuga… - Journal of …, 2021 - Elsevier
The essential goals of this present study are to elucidate the formation mechanism of ellagic
acid rich-blackberry, BBE,(Rubus fruticosus L.) and raspberry, RBE,(Rubus idaeus L.) …

Development of cell-SELEX technology and its application in cancer diagnosis and therapy

M Chen, Y Yu, F Jiang, J Zhou, Y Li, C Liang… - International journal of …, 2016 - mdpi.com
SELEX (systematic evolution of ligands by exponential enrichment) is a process involving
the progressive isolation of high selective ssDNA/RNA from a combinatorial single-stranded …

Cell-SELEX technology

S Ohuchi - BioResearch open access, 2012 - liebertpub.com
Aptamers are molecules identified from large combinatorial nucleic acid libraries by their
high affinity to target molecules. Due to a variety of desired properties, aptamers are …

Nano-gold mediated aptasensor for colorimetric monitoring of acrylamide: Smartphone readout strategy for on-site food control

Z Khoshbin, M Moeenfard, K Abnous, SM Taghdisi - Food Chemistry, 2023 - Elsevier
A simple aptasensor is embedded in the internal surface of a micropipette tip as the
aptasensor substrate for the label-free monitoring of acrylamide. The aptasensor is based on …