Innate immunity comprises several inflammation-related modulatory pathways which receive
signals from an array of membrane-bound and cytoplasmic pattern recognition receptors …

Simple Summary Cutaneous melanoma represents the most aggressive form of skin cancer
and its occurrence, development, and progression are based on the accumulation of several …

Over the past decade, immune checkpoint inhibitors (ICI) have revolutionized the treatment
of advanced melanoma and ensured significant improvement in overall survival versus …

Infectious and many non-infectious diseases share common molecular mechanisms. Among
them, oxidative stress and the subsequent inflammatory reaction are of particular note …

The crosstalk between Notch and MAPK pathway plays a role in MEK inhibitor resistance in
BRAF V600E metastatic melanoma (MM) and promotes migration in GNAQ Q209L uveal …

Cutaneous melanoma is an immunogenic highly heterogenic tumor characterized by poor
outcomes when it is diagnosed late. Therefore, immunotherapy in combination with other …

Simple Summary Melanoma cells reside in a complex stromal microenvironment, which is a
critical component of disease onset and progression. Mesenchymal or fibroblastic cell type …

Both infectious and non-infectious diseases can share common molecular mechanisms,
including oxidative stress and inflammation. External factors, such as bacterial or viral …

Background and objectives Vitexin is a natural flavonoid glycoside mainly extracted from the
leaves of vitex, which has a variety of physiological activities. For example, vitexin has …

The roots of Angelica dahurica have long been used as a traditional medicine in Korea to
treat various diseases such as toothache and cold. In this study, we investigated the effect of …