Although asthma has been considered as a single disease for years, recent studies have
increasingly focused on its heterogeneity. The characterization of this heterogeneity has …

Asthma | From Bronchoconstriction to Airways Inflammation and Remodeling | American
Journal of Respiratory and Critical Care Medicine ATS Journals Logo Official Publications …

While asthma is considered an inflammatory disorder of the conducting airways, it is
becoming increasingly apparent that the disease is heterogeneous with respect to …

Airway inflammation in severe asthma is not well characterized but may involve neutrophils.
We have compared induced sputum profiles in patients with asthma of varying severity and …

IgE plays an important role in allergic asthma. We hypothesized that reducing IgE in the
airway mucosa would reduce airway inflammation. Forty-five patients with mild to moderate …

In order to investigate the relationship between airways inflammation and disease severity,
and improve the understanding of persistent asthma, 74 asthmatics, with disease severity …

The use of exhaled nitric oxide measurements (FEno) in clinical practice is now coming of
age. There are a number of theoretical and practical factors which have brought this about …

This review is the synthesis of a working group on mild asthma. Mild asthma includes
intermittent and persistent mild asthma according to the Global Initiative for Asthma (GINA) …

Glucocorticoids are potent inhibitors of inflammatory processes and are widely used in the
treatment of asthma. The anti‐inflammatory effects are mediated either by direct binding of …

In airway diseases such as asthma and COPD, specific structural changes may be
observed, very likely secondary to an underlying inflammatory process. Although it is still …