Diversity of epigenetic features of the inactive X-chromosome in NK cells, dendritic cells, and macrophages
CM Syrett, V Sindhava, I Sierra, AH Dubin… - Frontiers in …, 2019 - frontiersin.org
In females, the long non-coding RNA Xist drives X-chromosome Inactivation (XCI) to
equalize X-linked gene dosage between sexes. Unlike other somatic cells, dynamic …
equalize X-linked gene dosage between sexes. Unlike other somatic cells, dynamic …
Severely impaired CTL killing is a feature of the neurological disorder Niemann-Pick disease type C1
D Castiblanco, JA Rudd-Schmidt… - Blood, The Journal …, 2022 - ashpublications.org
Niemann-Pick disease type C1 (NP-C1) is a rare lysosomal storage disorder resulting from
mutations in an endolysosomal cholesterol transporter, NPC1. Despite typically presenting …
mutations in an endolysosomal cholesterol transporter, NPC1. Despite typically presenting …
Adaptive NK Cells Rapidly Expand during Acute HIV Infection and Persist Despite Early Initiation of Antiretroviral Therapy
AC Hearps, J Zhou, PA Agius, P Ha, S Lee… - The Journal of …, 2024 - journals.aai.org
HIV is associated with NK cell dysfunction and expansion of adaptive-like NK cells that
persist despite antiretroviral therapy (ART). We investigated the timing of NK cell …
persist despite antiretroviral therapy (ART). We investigated the timing of NK cell …
Genotype characteristics and immunological indicator evaluation of 311 hemophagocytic lymphohistiocytosis cases in China
J Zhang, Y Sun, X Shi, R Zhang, Y Wang, J Xiao… - Orphanet journal of rare …, 2020 - Springer
Background Primary hemophagocytic lymphohistiocytosis (pHLH) is a genetic disorder that
is classically diagnosed by genetic testing. Secondary HLH (sHLH) is usually caused by …
is classically diagnosed by genetic testing. Secondary HLH (sHLH) is usually caused by …
Genetic susceptibility to EBV-related disease
MK Gandhi - Blood, The Journal of the American Society of …, 2023 - ashpublications.org
More than 90% of the general population show evidences of past infection of Epstein-Barr
virus (EBV). So why do only a few of us experience EBV-related disease? In this issue of …
virus (EBV). So why do only a few of us experience EBV-related disease? In this issue of …
The role of allogeneic hematopoietic stem cell transplantation and Epstein‐Barr virus infection on the treatment for child primary hemophagocytic lymphohistiocytosis …
T Cui, Y Wang, J Wang, J Zhang, Z Gao… - Pediatric …, 2020 - Wiley Online Library
XLP‐2 is known as a rare primary immunodeficiency disease, which is characterized by the
susceptibility to EBV infection and potential development into the pHLH. The existing studies …
susceptibility to EBV infection and potential development into the pHLH. The existing studies …