Organ‐on‐a‐chip platforms: a convergence of advanced materials, cells, and microscale technologies

S Ahadian, R Civitarese, D Bannerman… - Advanced …, 2018 - Wiley Online Library
Significant advances in biomaterials, stem cell biology, and microscale technologies have
enabled the fabrication of biologically relevant tissues and organs. Such tissues and organs …

Liver tissue engineering: challenges and opportunities

T Agarwal, B Subramanian, TK Maiti - Acs Biomaterials Science & …, 2019 - ACS Publications
Liver tissue engineering aims at the possibility of reproducing a fully functional organ for the
treatment of acute and chronic liver disorders. Approaches in this field endeavor to replace …

Metabolic Patterning on a Chip: Towards in vitro Liver Zonation of Primary Rat and Human Hepatocytes

YB Kang, J Eo, S Mert, ML Yarmush, OB Usta - Scientific reports, 2018 - nature.com
An important number of healthy and diseased tissues shows spatial variations in their
metabolic capacities across the tissue. The liver is a prime example of such heterogeneity …

Selection of natural biomaterials for micro‐tissue and organ‐on‐chip models

B Cecen, A Bal‐Ozturk, G Yasayan… - … Research Part A, 2022 - Wiley Online Library
The desired organ in micro‐tissue models of organ‐on‐a‐chip (OoC) devices dictates the
optimum biomaterials, divided into natural and synthetic biomaterials. They can resemble …

Placental model as an important tool to study maternal-fetal interface

BM Gonçalves, JB Graceli, PB da Rocha, HP Tilli… - Reproductive …, 2022 - Elsevier
The placenta is a temporary organ that plays critical roles at the maternal-fetal interface.
Normal development and function of the placenta is dependent on hormonal signaling …

[HTML][HTML] Human-scale tissues with patterned vascular networks by additive manufacturing of sacrificial sugar-protein composites

HM Eltaher, FE Abukunna, L Ruiz-Cantu, Z Stone… - Acta biomaterialia, 2020 - Elsevier
Combating necrosis, by supplying nutrients and removing waste, presents the major
challenge for engineering large three-dimensional (3D) tissues. Previous elegant work used …

Evaluation of drug carrier hepatotoxicity using primary cell culture models

G Kibar, S Dutta, K Rege, OB Usta - … : Nanotechnology, Biology and …, 2023 - Elsevier
This study aims to establish a primary rat hepatocyte culture model to evaluate dose-
dependent hepatotoxic effects of drug carriers (lipopolymer nanoparticles; LPNs) temporal …

Waste-to-wealth: American bullfrog skin-derived collagen for wound dressing applications

C Cimenoglu - 2021 - dr.ntu.edu.sg
Wound healing is a complex process in which four successive steps involve along with
various cell types, extracellular matrix proteins and growth factors. Successful wound …

[PDF][PDF] In-vitrothree dimensionalspheriodsfor personalized radiation therapy

Y Qiu - 2018 - ytqiu666.github.io
ABSTRACT X-ray radiation therapy can be used for to treat cancer for primary therapy of
localized tumors and for adjuvant and palliative therapy to relieve symptoms from later stage …