When released into biological fluids like blood or saliva, brain extracellular vesicles (EVs)
might provide a window into otherwise inaccessible tissue, contributing useful biomarkers of …

Cognitive dysfunction is a common adverse consequence of traumatic brain injury (TBI).
After brain injury, the brain and other organs trigger a series of complex metabolic changes …

As the SARS-CoV-2 pandemic continues, reports have demonstrated neurologic sequelae
following COVID-19 recovery. Mechanisms to explain long-term neurological sequelae are …

L1CAM is a transmembrane protein expressed on neurons that was presumed to be found
on neuron-derived extracellular vesicles (NDEVs) in human biofluids. We developed a …

The pathology of sepsis‐associated encephalopathy (SAE) is related to astrocyte‐
inflammation associated with aquaporin‐4 (AQP4). The aim here is to investigate the effects …

Traumatic brain injury (TBI) can initiate progressive injury responses, which are linked to
increased risk of neurodegenerative diseases known as “tauopathies.” Increased post-TBI …

Traumatic brain injury (TBI) is a heterogeneous condition, associated with diverse etiologies,
clinical presentations and degrees of severity, and may result in chronic neurobehavioral …

Introduction Objective and accessible markers for Alzheimer's disease (AD) and other
dementias are critically needed. Methods We identified NMDAR2A, a protein related to …

Extracellular vesicles (EVs) are bilayer membrane vesicles and act as key messengers in
intercellular communication. EVs can be secreted by both neurons and glial cells in the …

Exosome, a subpopulation of extracellular vesicles, plays diverse roles in various biological
processes. As one of the most abundant components of exosomes, exosomal proteins have …