Breast cancer development largely depends upon the essential contributions from the tumor
microenvironment, where several inflammatory cell populations (eg macrophages) …

Breast cancer is one of the leading causes of mortality in the females. Intensive efforts have
been made to understand the molecular mechanisms of pathogenesis of breast cancer. The …

Lung adenocarcinoma (LUAD) harboring EGFR mutations prevails in Asian population.
However, the inter-patient and intra-tumor heterogeneity has not been addressed at single …

Abstract S100A8/A9, a proinflammatory protein, is upregulated in inflammatory diseases,
and also has a tumor-promoting activity by the recruitment of myeloid cells and tumor cell …

Abstract Introduction Tumor-associated macrophages (TAMs) in breast cancer are
associated with a poor prognosis. Early studies of TAMs were largely limited to the pan …

Racial disparities in breast cancer incidence and outcome are a major health care
challenge. Patients in the black race group more likely present with an early onset and more …

Inflammation is an important feature of carcinogenesis. Tumor-associated macrophages
(TAMs) can be associated with either poor or improved prognosis, depending on their …

Background As crucial regulators of the immune response against pathogens, macrophages
have been extensively shown also to be important players in several diseases, including …

The role of macrophages in colorectal cancer tumorogenesis is complex because they can
both prevent and promote tumor development. We investigated CD68-positive cell infiltration …

Background Accumulation of tumor-infiltrating mast cells (MCs) predicts poor survival in
several cancers after resection. However, its effect on the prognosis of patients with …