The cryopyrin-associated periodic syndromes (CAPS) are usually caused by heterozygous
NLRP3 gene variants, resulting in excessive inflammasome activation with subsequent …

The cryopyrin-associated periodic syndrome (CAPS) is a severity spectrum of rare diseases.
CAPS comprises the three conditions previously described as familial cold autoinflammatory …

Background Diagnosing systemic juvenile idiopathic arthritis (SJIA) can be extremely
challenging if typical arthritis is lacking. A variety of biomarkers have been described for the …

Background Serum phagocyte-derived alarmins S100A8/9 and S100A12 are considered
useful for the assessment of inflammatory diseases. Our study evaluated the use of S100 …

Systemic juvenile idiopathic arthritis (sJIA) and its complication, macrophage activation
syndrome (sJIA-MAS), are rare but sometimes very serious or even critical diseases of …

Systemic juvenile idiopathic arthritis (SJIA) is an im-portant disease for primary care
physicians to keep in mind while managing a child with fever without an obvious source …

Juvenile idiopathic arthritis (JIA) represents a chronic, autoimmune, rheumatic
musculoskeletal disease with a diagnosis before 16 years of age. Chronic arthritis is a …

Background Seronegative joint diseases are characterized by a lack of well-defined
biomarkers since autoantibodies are not elevated. Calprotectin (S100A8/A9) is a damage …

Systemic juvenile idiopathic arthritis is a chronic pediatric inflammatory disease of unknown
etiology, characterized by fever, rash, hepatosplenomegaly, serositis, and arthritis. We …

Objective. The aim of this study was to present the genetic and clinical data of the largest
cohort of Turkish cryopyrinassociated periodic syndromes (CAPS) patients. Methods. This is …