Adaptive homeostasis is “the transient expansion or contraction of the homeostatic range for
any given physiological parameter in response to exposure to sub‐toxic, non‐damaging …

Here we summarize the latest data on genetic and epigenetic contributions to human aging
and longevity. Whereas environmental and lifestyle factors are important at younger ages …

Aging is a complex and highly variable process. Heritability of longevity among humans and
other species is low, and this finding has given rise to the idea that it may be futile to search …

Ageing is a complex but universal phenomenon that progressively challenges the
homeostasis network and finally leads to the dysfunction of organisms and even death …

Metabolic syndrome (MetS) is a cluster of risk factors that lead to microvascular dysfunction
and chronic cerebral hypoperfusion (CCH). Long-standing reduction in oxygen and energy …

Aging is the process of growing older or changing over time [1]. In other words, aging is the
entire sequence of changes during ontogenesis of an individual organism during its lifetime …

In this study we explored the association between aging-related phenotypes previously
reported to predict survival in old age and variation in 77 genes from the DNA repair …

长寿是一个复杂的特征, 因遗传, 环境等因素的差异而不同, 理想情况下主要取决于衰老速率.
相关分子机制多种多样, 主要有生长激素(GH) 和胰岛素样生长因子1 (IGF⁃ 1) 途径, Forkhead …

Aging is the process of growing older or changing over time [1]. In other words, aging is the
entire sequence of changes during ontogenesis of an individual organism during its lifetime …

The Hamilton Anxiety Rating Scale (HARS; Hamilton 1959) is a 14-item clinician-rated
measure of the severity of perceived anxiety symptoms. It is originally designed to assess …