Three types of highly promising small RNA therapeutics, namely, small interfering RNAs
(siRNAs), microRNAs (miRNAs) and the RNA subtype of antisense oligonucleotides (ASOs) …

Abstract The 2022 Nucleic Acids Research Database Issue contains 185 papers, including
87 papers reporting on new databases and 85 updates from resources previously published …

Circular RNAs (circRNAs) are stable, enclosed, non-coding RNA molecules with dynamic
regulatory propensity. Their biogenesis involves a back-splicing process, forming a highly …

MicroRNAs (miRNAs) are small non-coding RNAs (18–26 nucleotides) that regulate gene
expression by interacting with target mRNAs, affecting various physiological and …

Left ventricular pressure overload (LVPO) can lead to heart failure with a preserved ejection
fraction (HFpEF) and LV chamber stiffness (LV K c) is a hallmark. This project tested the …

Our previous research revealed a key microRNA signature that is associated with
spaceflight that can be used as a biomarker and to develop countermeasure treatments to …

Objective Patients with ovarian cancer (OC) may develop anti‐Yo‐associated
paraneoplastic cerebellar degeneration (PCD)—a cerebellar ataxia associated with tumor …

Recent advances in high-throughput molecular methods have led to an extraordinary
volume of genomics data. Simultaneously, the progress in the computational implementation …

Abstract microRNAs (miRNAs) are central post-transcriptional gene expression regulators in
healthy and diseased states. Despite decades of effort, deciphering miRNA targets remains …

This study explores the role of LINC00839 and its potential interaction with the miR-195-
5p/cyclin E1 (CCNE1) axis in oral squamous cell carcinoma (OSCC). Using The Cancer …