Endocrine-disrupting chemicals: implications for human health

LG Kahn, C Philippat, SF Nakayama… - The lancet Diabetes & …, 2020 - thelancet.com
Since reports published in 2015 and 2016 identified 15 probable exposure–outcome
associations, there has been an increase in studies in humans of exposure to endocrine …

Environmental endocrine-disrupting chemical exposure: role in non-communicable diseases

M Kumar, DK Sarma, S Shubham, M Kumawat… - Frontiers in public …, 2020 - frontiersin.org
The exponential growth of pollutant discharges into the environment due to increasing
industrial and agricultural activities is a rising threat for human health and a biggest concern …

Re‐evaluation of the risks to public health related to the presence of bisphenol A (BPA) in foodstuffs

EFSA Panel on Food Contact Materials … - EFSA …, 2023 - Wiley Online Library
In 2015, EFSA established a temporary tolerable daily intake (t‐TDI) for BPA of 4 μg/kg body
weight (bw) per day. In 2016, the European Commission mandated EFSA to re‐evaluate the …

Endocrine disrupting chemicals in polycystic ovary syndrome: the relevant role of the theca and granulosa cells in the pathogenesis of the ovarian dysfunction

M Jozkowiak, H Piotrowska-Kempisty, D Kobylarek… - Cells, 2022 - mdpi.com
Polycystic ovary syndrome (PCOS) is the most common heterogeneous endocrine disorder
among women of reproductive age. The pathogenesis of PCOS remains elusive; however …

[HTML][HTML] Exposure to bisphenol A and its analogs and polycystic ovarian syndrome in women of childbearing age: A multicenter case-control study

W Zhan, W Tang, X Shen, H Xu, J Zhang - Chemosphere, 2023 - Elsevier
Background/objectives In recent years, the reproductive toxicity of new bisphenol analogs
has garnered much interest, but it remains to be determined whether bisphenol analogs …

The role of genetics, epigenetics and lifestyle in polycystic ovary syndrome development: the state of the art

V Bruni, A Capozzi, S Lello - Reproductive Sciences, 2022 - Springer
Polycystic ovary syndrome (PCOS) is an endocrine-metabolic disease affecting about 20–
25% of women in reproductive age. Different mechanisms could contribute to the …

Polycystic ovary syndrome and endocrine disruptors (bisphenols, parabens, and triclosan)—a systematic review

T Srnovršnik, I Virant-Klun, B Pinter - Life, 2023 - mdpi.com
Exposure to endocrine disrupting chemicals (EDCs) can result in alterations of the female
reproductive system, including polycystic ovary syndrome (PCOS). The aim of this review …

Detrimental effects of bisphenol compounds on physiology and reproduction in fish: a literature review

M Faheem, RK Bhandari - Environmental Toxicology and Pharmacology, 2021 - Elsevier
Bisphenol-A is one of the most studied endocrine-chemicals, which is widely used all over
the world in plastic manufacture. Because of its extensive use, it has become one of the most …

The epigenetic impacts of endocrine disruptors on female reproduction across generations

S Rattan, JA Flaws - Biology of reproduction, 2019 - academic.oup.com
Humans and animals are repeatedly exposed to endocrine disruptors, many of which are
ubiquitous in the environment. Endocrine disruptors interfere with hormone action; thus …

Review on bisphenol A and the risk of polycystic ovarian syndrome: an insight from endocrine and gene expression

R Mukhopadhyay, NB Prabhu, SP Kabekkodu… - … Science and Pollution …, 2022 - Springer
Bisphenol A (BPA) is one of the most widely studied endocrine disrupting chemicals
because of its structural similarity to 17-β estradiol; its ability to bind as an agonist/antagonist …