Design and translation of injectable biomaterials

M Nguyen, M Karkanitsa, KL Christman - Nature Reviews …, 2024 - nature.com
Injectable biomaterials, including bulk materials and particulate materials, can be delivered
in a minimally invasive way and may provide alternative treatment options for conditions that …

Recent advances in soft biological tissue manipulating technologies

Z Liu, Z Liao, D Wang, C Wang, C Song, H Li… - Chinese journal of …, 2022 - Springer
Biological soft tissues manipulation, including conventional (mechanical) and
nonconventional (laser, waterjet and ultrasonic) processes, is critically required in most …

Bevel angle study of flexible hollow needle insertion into biological mimetic soft-gel: Simulation and experimental validation

MG Jushiddi, RM Cahalane, M Byrne, A Mani… - Journal of the …, 2020 - Elsevier
Background A thorough understanding of cutting-edge geometry and cutting forces of hollow
biopsy needles are required to optimise needle tip design to improve fine needle aspiration …

Novel design of honeybee-inspired needles for percutaneous procedure

M Sahlabadi, P Hutapea - Bioinspiration & biomimetics, 2018 - iopscience.iop.org
The focus of this paper is to present new designs of innovative bioinspired needles to be
used during percutaneous procedures. Insect stingers have been known to easily penetrate …

Simulation of biopsy bevel-tipped needle insertion into soft-gel

MG Jushiddi, JJE Mulvihill, D Chovan, A Mani… - Computers in biology …, 2019 - Elsevier
Planning and practice of surgical procedures can be improved through the use of modelling.
This study provides an insight into the biopsy needle (ie hollow cannula) and needle-tissue …

Backflow modeling in nanofluid infusion and analysis of its effects on heat induced damage during magnetic hyperthermia

Y Tang, J Zou, RCC Flesch, T Jin - Applied Mathematical Modelling, 2023 - Elsevier
Although targeted magnetic hyperthermia has been proven to be an effective tumor ablation
technique, its use in clinical applications is still scarce particularly due to the difficulty in …

Insertion mechanics of bioinspired needles into soft tissues

M Sahlabadi, S Khodaei, K Jezler… - … Invasive Therapy & …, 2018 - Taylor & Francis
Introduction: Most studies to date confirm that any increase in the needle insertion force
increases the damage to the tissue. When it comes to brain tissue, even minor damage can …

Mechanical characterization of a fiberoptic microneedle device for controlled delivery of fluids and photothermal excitation

F Akhter, GNW Bascos, M Canelas, B Griffin… - Journal of the …, 2020 - Elsevier
Current clinical approaches for treating pancreatic cancer have been demonstrated as
ineffective at improving midterm survival. A primary obstacle to local drug delivery is the …

Cone cracks in tissue-mimicking hydrogels during hypodermic needle insertion: the role of water content

M Muthukumar, MS Bobji, KRY Simha - Soft Matter, 2022 - pubs.rsc.org
Needle insertion into soft biological tissues is a common process in various surgical
procedures. During insertion, soft biological tissues with different water contents undergo …

A novel material point method (MPM) based needle-tissue interaction model

M Li, Y Lei, D Gao, Y Hu, X Zhang - Computer Methods in …, 2021 - Taylor & Francis
Needle-tissue interaction model is essential to tissue deformation prediction, interaction
force analysis and needle path planning system. Traditional FEM based needle-tissue …