Multi-arm RNA junctions encoding molecular logic unconstrained by input sequence for versatile cell-free diagnostics

D Ma, Y Li, K Wu, Z Yan, AA Tang… - Nature biomedical …, 2022 - nature.com
Applications of RNA-based molecular logic have been hampered by sequence constraints
imposed on the input and output of the circuits. Here we show that the sequence constraints …

HIV-1 molecular diversity in Brazil unveiled by 10 years of sampling by the national genotyping network

T Gräf, G Bello, P Andrade, I Arantes, JM Pereira… - Scientific Reports, 2021 - nature.com
HIV-1 has diversified into several subtypes and recombinant forms that are heterogeneously
spread around the world. Understanding the distribution of viral variants and their temporal …

Identification of new HIV-1 circulating recombinant forms CRF81_cpx and CRF99_BF1 in Central Western Brazil and of unique BF1 recombinant forms

MNG Reis, ML Guimarães, G Bello… - Frontiers in …, 2019 - frontiersin.org
Intersubtype recombinants classified as circulating recombinant forms (CRFs) or unique
recombinant forms (URFs) have been shown to play an important role in the complex and …

Estimating HIV-1 genetic diversity in Brazil through next-generation sequencing

BM Alves, JD Siqueira, IM Prellwitz… - Frontiers in …, 2019 - frontiersin.org
Approximately 36.7 million people were living with the human immunodeficiency virus (HIV)
at the end of 2016 according to UNAIDS, representing a global prevalence rate of 0.8%. In …

Molecular epidemiology of the HIV epidemic in three German metropolitan regions–Cologne/Bonn, Munich and Hannover, 1999–2016

M Stecher, A Chaillon, J Eberle, GMN Behrens… - Scientific reports, 2018 - nature.com
Using HIV sequence data to characterize clusters of HIV transmission may provide insight
into the epidemic. Phylogenetic and network analyses were performed to infer putative …

HIV-1 genetic diversity and transmitted drug resistance to integrase strand transfer inhibitors among recently diagnosed adults in Porto Alegre, South Brazil

CC Nunes, A Sita, L Mallmann… - Journal of …, 2022 - academic.oup.com
Objectives The HIV-1 genetic diversity and the presence of transmitted drug resistance
mutations (TDRMs) against integrase strand transfer inhibitors (INSTIs) were assessed …

Gut microbiome profiles and associated metabolic pathways in HIV-infected treatment-naïve patients

WM do Nascimento, A Machiavelli, LGE Ferreira… - Cells, 2021 - mdpi.com
The normal composition of the intestinal microbiota is a key factor for maintaining healthy
homeostasis, and accordingly, dysbiosis is well known to be present in HIV-1 patients. This …

[HTML][HTML] Tracing the Dispersal Pathway of HIV-1 Subtype C to Bahia: Phylogenetic Connections to Southern Brazil

D Polita, L de Moraes, M Giovanetti… - Viruses, 2024 - mdpi.com
The HIV-1 epidemic in Brazil is predominantly characterized by subtype B, except in the
southern states, where subtype C (HIV-1C) is more prevalent. Continuous monitoring of this …

Inferring population dynamics of HIV-1 subtype C epidemics in Eastern Africa and Southern Brazil applying different Bayesian phylodynamics approaches

D Mir, T Gräf, S Esteves de Matos Almeida, AR Pinto… - Scientific Reports, 2018 - nature.com
Abstract The subtype C Eastern Africa clade (CEA), a particularly successful HIV-1 subtype
C lineage, has seeded several sub-epidemics in Eastern African countries and Southern …

Genotyping and Antiretroviral Drug Resistance Mutations among HIV Patients in Southern Santa Catarina, Brazil

CE Mendes Marcon, AD Schlindwein… - Current HIV …, 2024 - benthamdirect.com
Introduction Therapeutic measures have been successful in increasing survival rates and
quality of life of HIV/AIDS-infected people. However, some people fail to respond to …