The role of GPCRs in bone diseases and dysfunctions
The superfamily of G protein-coupled receptors (GPCRs) contains immense structural and
functional diversity and mediates a myriad of biological processes upon activation by …
functional diversity and mediates a myriad of biological processes upon activation by …
The role of chemerin in metabolic and cardiovascular disease: a literature review of its physiology and pathology from a nutritional perspective
Chemerin is a novel adipokine that plays a major role in adipogenesis and lipid metabolism.
It also induces inflammation and affects insulin signaling, steroidogenesis and …
It also induces inflammation and affects insulin signaling, steroidogenesis and …
Associations between exposure to a mixture of phenols, parabens, and phthalates and sex steroid hormones in children 6–19 years from NHANES, 2013–2016
P Hu, C Pan, W Su, A Vinturache, Y Hu, X Dong… - Science of The Total …, 2022 - Elsevier
Background Humans are typically exposed to mixtures of environmental endocrine–
disrupting chemicals simultaneously, but most studies have considered only a single …
disrupting chemicals simultaneously, but most studies have considered only a single …
Associations between pyrethroid exposure and serum sex steroid hormones in adults: Findings from a nationally representative sample
H Xu, Y Bo - Chemosphere, 2022 - Elsevier
Background Pyrethroids have been considered as potential endocrine-disrupting chemicals
and have been shown to be associated with endocrine-related health outcomes. However …
and have been shown to be associated with endocrine-related health outcomes. However …
Cerium oxide nanoparticles regulate osteoclast differentiation bidirectionally by modulating the cellular production of reactive oxygen species
K Yuan, J Mei, D Shao, F Zhou, H Qiao… - International journal …, 2020 - Taylor & Francis
Background Cerium oxide nanoparticles (CeO2NPs) are potent scavengers of cellular
reactive oxygen species (ROS). Their antioxidant properties make CeO2NPs promising …
reactive oxygen species (ROS). Their antioxidant properties make CeO2NPs promising …
Chemerin: a functional adipokine in reproductive health and diseases
M Yu, Y Yang, C Huang, L Ge, L Xue, Z Xiao, T Xiao… - Biomedicines, 2022 - mdpi.com
As a multifaceted adipokine, chemerin has been found to perform functions vital for
immunity, adiposity, and metabolism through its three known receptors (chemokine-like …
immunity, adiposity, and metabolism through its three known receptors (chemokine-like …
Independent and combined associations of urinary arsenic exposure and serum sex steroid hormones among 6-19-year old children and adolescents in NHANES …
Y Zhang, H Xing, Z Hu, W Xu, Y Tang, J Zhang… - Science of The Total …, 2023 - Elsevier
Arsenic exposure may disrupt sex steroid hormones, causing endocrine disruption.
However, human evidence is limited and inconsistent, especially for children and …
However, human evidence is limited and inconsistent, especially for children and …
Adipokines as targets in musculoskeletal immune and inflammatory diseases
M González-Rodríguez, C Ruiz-Fernández… - Drug Discovery …, 2022 - Elsevier
Adipokines are the principal mediators in adipose signaling. Nevertheless, besides their role
in energy storage, these molecules can be produced by other cells, such as immune cells or …
in energy storage, these molecules can be produced by other cells, such as immune cells or …
Chemerin located in bone marrow promotes osteogenic differentiation and bone formation via Akt/Gsk3β/β‐catenin axis in mice
J Li, T Zhang, C Huang, M Xu, W Xie… - Journal of Cellular …, 2021 - Wiley Online Library
Chemerin, a secreted protein mainly produced by adipocytes and hepatocytes, plays a
variety of roles in endocrine or paracrine signaling. As reported in human epidemiology …
variety of roles in endocrine or paracrine signaling. As reported in human epidemiology …
[HTML][HTML] Loss of chemerin triggers bone remodeling in vivo and in vitro
L Han, Y Zhang, S Wan, Q Wei, W Shang, G Huang… - Molecular …, 2021 - Elsevier
Objective It was reported that chemerin as an adipocyte-secreted protein could regulate
bone resorption and bone formation. However, the specific molecular and gene mechanism …
bone resorption and bone formation. However, the specific molecular and gene mechanism …