Rheumatoid arthritis (RA) is a systemic poly-articular chronic autoimmune joint disease that
mainly damages the hands and feet, which affects 0.5% to 1.0% of the population …

15‐Deoxy‐∆‐12, 14‐prostaglandin J2 (15d‐PGJ2), a natural peroxisome proliferator‐
activated receptor‐γ (PPAR‐γ) agonist, has been explored in some detail over the last 20 …

Metabolic health and immune function are intimately connected via diet and the microbiota.
Nearly 90% of all immune cells in the body are associated with the gastrointestinal tract and …

Rheumatoid arthritis is one of the most prevalent, chronic, inflammatory disorders involving
multiple articular and extra-articular complications. Immune deregulation owing to a …

Natural or synthetic ligands for peroxisome proliferator-activated receptor gamma (PPAR-γ)
represent an interesting tool for pharmacological interventions to treat inflammatory …

Rheumatoid arthritis and periodontitis are chronic inflammatory diseases which has been
closely associated due to the nature of immune-inflammatory imbalance response …

Pioglitazone, an agonist at peroxisome proliferator-activated receptor gamma, is FDA-
approved for the treatment of insulin resistance in type 2 diabetes. Numerous studies in …

Resolvins, are specialized pro-resolving mediators (SPMs) derived from n-3
polyunsaturated fatty acids. They contribute actively to the resolution of inflammation, but …

Rheumatoid arthritis (RA) is an autoimmune disorder that is slow progressive destruction of
the joints and is caused by autoantibodies that target a variety of organs thereby leading to …

Gout arthritis (GA) is a painful inflammatory disease in response to monosodium urate
(MSU) crystals in the joints. 15deoxy-Δ12, 14-prostaglandin J2 (15d-PGJ2) is a natural …