Galectin-9 as a biomarker of disease severity

P Moar, R Tandon - Cellular immunology, 2021 - Elsevier
Abstract Galectin-9 (Gal-9) is a β-galactoside binding lectin known for its immunomodulatory
role in various microbial infections. Gal-9 is expressed in all organ systems and localized in …

The potential role of growth differentiation factor 15 in COVID-19: a corollary subjective effect or not?

AO Babalghith, HM Al-Kuraishy, AI Al-Gareeb… - Diagnostics, 2022 - mdpi.com
Coronavirus disease 2019 (COVID-19) is primarily caused by various forms of severe acute
respiratory syndrome coronavirus type 2 (SARS-CoV-2) variants. COVID-19 is characterized …

[HTML][HTML] Multisystem inflammatory syndrome in children is driven by zonulin-dependent loss of gut mucosal barrier

LM Yonker, T Gilboa, AF Ogata… - The Journal of …, 2021 - Am Soc Clin Investig
Multisystem inflammatory syndrome in children (MIS-C) occurs during or recently following
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and is …

Distinct systemic and mucosal immune responses during acute SARS-CoV-2 infection

N Smith, P Goncalves, B Charbit, L Grzelak… - Nature …, 2021 - nature.com
Coordinated local mucosal and systemic immune responses following severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) infection either protect against …

Persistence, magnitude, and patterns of postacute symptoms and quality of life following onset of SARS-CoV-2 infection: cohort description and approaches for …

MJ Peluso, JD Kelly, S Lu, SA Goldberg… - Open forum …, 2022 - academic.oup.com
Background There is mounting evidence for the presence of postacute sequelae of severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection (PASC), but there is …

Could Perturbation of Gut Microbiota Possibly Exacerbate the Severity of COVID-19 via Cytokine Storm?

R Vignesh, CR Swathirajan, ZH Tun… - Frontiers in …, 2021 - frontiersin.org
1 Preclinical Department, Faculty of Medicine, Royal College of Medicine Perak, Universiti
Kuala Lumpur, Ipoh, Malaysia, 2 Infectious Diseases Laboratory, YR Gaitonde Centre for …

[HTML][HTML] Increased LPS levels coexist with systemic inflammation and result in monocyte activation in severe COVID-19 patients

PC Teixeira, GP Dorneles, PC Santana Filho… - International …, 2021 - Elsevier
Mucosal barrier alterations may play a role in the pathogenesis of several diseases,
including COVID-19. In this study we evaluate the association between bacterial …

Plasma microbiome in COVID-19 subjects: An indicator of gut barrier defects and dysbiosis

R Prasad, MJ Patton, JL Floyd, S Fortmann… - International Journal of …, 2022 - mdpi.com
The gut is a well-established route of infection and target for viral damage by SARS-CoV-2.
This is supported by the clinical observation that about half of COVID-19 patients exhibit …

Coping with stress: the mitokine GDF-15 as a biomarker of COVID-19 severity

DS Ahmed, S Isnard, C Berini, J Lin, JP Routy… - Frontiers in …, 2022 - frontiersin.org
Growth differentiation factor 15 (GDF-15) is a transforming growth factor (TGF)-β superfamily
cytokine that plays a central role in metabolism regulation. Produced in response to …

[HTML][HTML] Rapid implementation of a cohort for the study of post-acute sequelae of SARS-CoV-2 infection/COVID-19

MJ Peluso, JD Kelly, S Lu, SA Goldberg, MC Davidson… - MedRxiv, 2021 - ncbi.nlm.nih.gov
BACKGROUND: As the coronavirus disease 2019 (COVID-19) pandemic continues and
millions remain vulnerable to infection with severe acute respiratory syndrome-coronavirus …