As the resident immune cells in the central nervous system (CNS), microglia orchestrate
immune responses and dynamically sculpt neural circuits in the CNS. Microglial dysfunction …

The crosstalk between the nervous and immune systems has gained increasing attention for
its emerging role in neurological diseases. Radiation-induced brain injury (RIBI) remains the …

Cre/loxP technology has revolutionized genetic studies and allowed for spatial and temporal
control of gene expression in specific cell types. Microglial biology has particularly benefited …

The infection of the central nervous system (CNS) with neurotropic viruses induces
neuroinflammation and is associated with the development of neuroinflammatory and …

Potassium channels are widespread over all kingdoms and play an important role in the
maintenance of cellular ionic homeostasis. Kv1. 3 is a voltage-gated potassium channel of …

Background Inflammation contributes to the poor prognosis of intracerebral hemorrhage
(ICH). Intermittent fasting (IF) has been shown to be protective against inflammation in …

The recent proliferation of new Cre and CreER recombinase lines provides researchers with
a diverse toolkit to study microglial gene function. To determine how best to apply these …

Introduction The inositol polyphosphate‐5‐phosphatase D (INPP5D) gene encodes a dual‐
specificity phosphatase that can dephosphorylate both phospholipids and phosphoproteins …

In the medial prefrontal cortex (PFC), chronic stress reduces synaptic expression of
glutamate receptors, leading to decreased excitatory signaling from layer V pyramidal …

Neurons, astrocytes and oligodendrocytes locally regulate protein translation within distal
processes. Here, we tested whether there is regulated local translation within peripheral …