Integrins in the spotlight of cancer

D Bianconi, M Unseld, GW Prager - International journal of molecular …, 2016 - mdpi.com
Integrins are heterodimeric cell surface receptors that bind to different extracellular ligands
depending on their composition and regulate all processes which enable multicellular life. In …

Plant viruses and bacteriophages for drug delivery in medicine and biotechnology

AE Czapar, NF Steinmetz - Current opinion in chemical biology, 2017 - Elsevier
Highlights•Plant viruses and bacteriophages can be regarded as natural nanoparticles.•Viral
nanoparticles are utilized in nanotechnology targeting diverse applications.•Viral capsids …

Potato virus X, a filamentous plant viral nanoparticle for doxorubicin delivery in cancer therapy

DHT Le, KL Lee, S Shukla, U Commandeur… - Nanoscale, 2017 - pubs.rsc.org
Plant viral nanoparticles (VNPs) are a novel class of nanocarriers with implications for drug
delivery in cancer therapy. VNPs are characterized by their highly symmetrical nanoscale …

Plant virus-based materials for biomedical applications: Trends and prospects

S Eiben, C Koch, K Altintoprak, A Southan… - Advanced drug delivery …, 2019 - Elsevier
Nanomaterials composed of plant viral components are finding their way into medical
technology and health care, as they offer singular properties. Precisely shaped, tailored …

Hierarchical self-assembly of responsive organoplatinum (II) metallacycle–TMV complexes with turn-on fluorescence

Y Tian, X Yan, ML Saha, Z Niu… - Journal of the American …, 2016 - ACS Publications
Here we report that the rod-like tobacco mosaic virus (TMV), having a negatively charged
surface, can be assembled into three-dimensional micrometer-sized bundle-like …

The pharmacology of plant virus nanoparticles

CI Nkanga, NF Steinmetz - Virology, 2021 - Elsevier
The application of nanoparticles for medical purposes has made enormous strides in
providing new solutions to health problems. The observation that plant virus-based …

Integration of cell-penetrating peptides with rod-like bionanoparticles: virus-inspired gene-silencing technology

Y Tian, M Zhou, H Shi, S Gao, G Xie, M Zhu, M Wu… - Nano Letters, 2018 - ACS Publications
Inspired by the high gene transfer efficiency of viral vectors and to avoid side effects, we
present here a 1D rod-like gene-silencing vector based on a plant virus. By decorating the …

Cancer theranostic applications of albumin-coated tobacco mosaic virus nanoparticles

AS Pitek, H Hu, S Shukla… - ACS applied materials & …, 2018 - ACS Publications
Nanotechnology holds great promise in cancer drug delivery, and of particular interest are
theranostic approaches in which drug delivery and imaging are integrated. In this work, we …

Application of plant viruses as a biotemplate for nanomaterial fabrication

Y Zhang, Y Dong, J Zhou, X Li, F Wang - Molecules, 2018 - mdpi.com
Viruses are widely used to fabricate nanomaterials in the field of nanotechnology. Plant
viruses are of great interest to the nanotechnology field because of their symmetry …

Advances of structural design and biomedical applications of tobacco mosaic virus coat protein

J Zhang, H He, F Zeng, M Du, D Huang… - Advanced …, 2024 - Wiley Online Library
Recognized as the primary RNA virus to be categorized and extensively studied, the
tobacco mosaic virus (TMV) is foundational to advancements in virology, molecular biology …