Carbapenem resistance: a review

FS Codjoe, ES Donkor - Medical Sciences, 2017 - mdpi.com
Carbapenem resistance is a major and an on-going public health problem globally. It occurs
mainly among Gram-negative pathogens such as Klebsiella pneumoniae, Pseudomonas …

Emerging antimicrobial-resistant high-risk Klebsiella pneumoniae clones ST307 and ST147

G Peirano, L Chen, BN Kreiswirth… - Antimicrobial agents and …, 2020 - Am Soc Microbiol
There is an enormous global public health burden due to antimicrobial-resistant (AMR)
Klebsiella pneumoniae high-risk clones. K. pneumoniae ST307 and ST147 are recent …

Plasmid evolution in carbapenemase‐producing Enterobacteriaceae: a review

K Kopotsa, J Osei Sekyere… - Annals of the New York …, 2019 - Wiley Online Library
Carbapenem‐resistant Enterobacteriaceae (CRE) have been listed by the WHO as high‐
priority pathogens owing to their high association with mortalities and morbidities …

Klebsiella oxytoca causes colonization resistance against multidrug-resistant K. pneumoniae in the gut via cooperative carbohydrate competition

L Osbelt, M Wende, É Almási, E Derksen… - Cell host & …, 2021 - cell.com
Gut colonization with multidrug-resistant (MDR) bacteria enhances the risk of bloodstream
infections in susceptible individuals. We demonstrate highly variable degrees of ex vivo …

Correlation between antimicrobial resistance and biofilm formation capability among Klebsiella pneumoniae strains isolated from hospitalized patients in Iran

S Shadkam, HR Goli, B Mirzaei, M Gholami… - Annals of Clinical …, 2021 - Springer
Background Klebsiella pneumoniae is a common cause of nosocomial infections. Antibiotic
resistance and ability to form biofilm, as two key virulence factors of K. pneumoniae, are …

[HTML][HTML] Carbapenemase-producing bacteria in food-producing animals, wildlife and environment: A challenge for human health

S Bonardi, R Pitino - Italian journal of food safety, 2019 - ncbi.nlm.nih.gov
Antimicrobial resistance is an increasing global health problem and one of the major
concerns for economic impacts worldwide. Recently, resistance against carbapenems …

Has resistance to chlorhexidine increased among clinically-relevant bacteria? A systematic review of time course and subpopulation data

S Buxser - PLoS One, 2021 - journals.plos.org
Chlorhexidine (CHX) was introduced for use as an antimicrobial more than 70 years ago.
CHX has been and continues to be used broadly for disinfecting surfaces in medical and …

Multidrug-Resistant Klebsiella pneumoniae Causing Severe Infections in the Neuro-ICU

NK Fursova, EI Astashkin, ON Ershova… - Antibiotics, 2021 - mdpi.com
The purpose of this study was the identification of genetic lineages and antimicrobial
resistance (AMR) and virulence genes in Klebsiella pneumoniae isolates associated with …

Pathogenomics and Evolutionary Epidemiology of Multi-Drug Resistant Clinical Klebsiella pneumoniae Isolated from Pretoria, South Africa

NM Mbelle, C Feldman, JO Sekyere, NE Maningi… - Scientific reports, 2020 - nature.com
Antibiotic-resistant Klebsiella pneumoniae is increasingly being implicated in invasive
infections worldwide with high mortalities. Forty-two multidrug resistant (MDR) K …

Emerging strategies to combat β-lactamase producing ESKAPE pathogens

CO Vrancianu, I Gheorghe, EG Dobre, IC Barbu… - International journal of …, 2020 - mdpi.com
Since the discovery of penicillin by Alexander Fleming in 1929 as a therapeutic agent
against staphylococci, β-lactam antibiotics (BLAs) remained the most successful antibiotic …