[HTML][HTML] Human milk oligosaccharides: Shaping the infant gut microbiota and supporting health

C Walsh, JA Lane, D van Sinderen… - Journal of Functional …, 2020 - Elsevier
Human milk oligosaccharides (HMO) are complex sugars which are found in breast milk at
significant concentrations and with unique structural diversity. These sugars are the fourth …

Altered composition and function of intestinal microbiota in autism spectrum disorders: a systematic review

F Liu, J Li, F Wu, H Zheng, Q Peng, H Zhou - Translational psychiatry, 2019 - nature.com
At present, the pathophysiology of autism spectrum disorder (ASD) remains unclear.
Increasing evidence suggested that gut microbiota plays a critical role in gastrointestinal …

Bifidobacterium infantis treatment promotes weight gain in Bangladeshi infants with severe acute malnutrition

MJ Barratt, S Nuzhat, K Ahsan, SA Frese… - Science Translational …, 2022 - science.org
Disrupted development of the gut microbiota is a contributing cause of childhood
malnutrition. Bifidobacterium longum subspecies infantis is a prominent early colonizer of …

The role of the intestinal microbiota in type 1 diabetes mellitus

M Knip, H Siljander - Nature Reviews Endocrinology, 2016 - nature.com
Type 1 diabetes mellitus (T1DM) is a chronic immune-mediated disease with a subclinical
prodromal period, characterized by selective loss of insulin-producing-β cells in the …

Human milk oligosaccharides influence neonatal mucosal and systemic immunity

SM Donovan, SS Comstock - Annals of Nutrition and Metabolism, 2016 - karger.com
The immune system of the infant is functionally immature and naïve. Human milk contains
bioactive proteins, lipids, and carbohydrates that protect the newborn and stimulate innate …

Intestinal microbiota development and gestational age in preterm neonates

K Korpela, EW Blakstad, SJ Moltu, K Strømmen… - Scientific reports, 2018 - nature.com
The intestinal microbiota is an important contributor to the health of preterm infants, and may
be destabilized by a number of environmental factors and treatment modalities. How to …

Pilot study of probiotic/colostrum supplementation on gut function in children with autism and gastrointestinal symptoms

MR Sanctuary, JN Kain, SY Chen, K Kalanetra… - PloS one, 2019 - journals.plos.org
Over half of all children with autism spectrum disorders (ASD) have gastrointestinal (GI) co-
morbidities including chronic constipation, diarrhea, and irritable bowel syndrome. The …

No vacancy: how beneficial microbes cooperate with immunity to provide colonization resistance to pathogens

M Sassone-Corsi, M Raffatellu - The Journal of Immunology, 2015 - journals.aai.org
The mammalian intestine harbors a community of trillions of microbes, collectively known as
the gut microbiota, which coevolved with the host in a mutually beneficial relationship …

Breast milk oligosaccharides: structure-function relationships in the neonate

JT Smilowitz, CB Lebrilla, DA Mills… - Annual review of …, 2014 - annualreviews.org
In addition to providing complete postnatal nutrition, breast milk is a complex biofluid that
delivers bioactive components for the growth and development of the intestinal and immune …

Molecular strategies for the utilisation of human milk oligosaccharides by infant gut-associated bacteria

LJ Kiely, K Busca, JA Lane… - FEMS Microbiology …, 2023 - academic.oup.com
A number of bacterial species are found in high abundance in the faeces of healthy breast-
fed infants, an occurrence that is understood to be, at least in part, due to the ability of these …