Purpose Gut microbiota regulate intestinal function and health. However, mounting evidence
indicates that they can also influence the immune and nervous systems and vice versa. This …

Autism spectrum disorders (ASDs) are pervasive neurodevelopmental disorders,
characterized by impairments in social interaction and communication and the presence of …

Background Mast cell activation is thought to be involved in visceral hypersensitivity, one of
the main characteristics of the irritable bowel syndrome (IBS). A study was therefore …

Background Irritable bowel syndrome (IBS) and functional dyspepsia (FD) are common
functional disorders without defined pathology. Mast cells and eosinophils interact with T …

OBJECTIVES: The pathogenesis of irritable bowel syndrome (IBS) is poorly understood.
One contributory factor may be low-grade mucosal inflammation, perhaps initiated by the …

Gastric cancer, one of the most common malignancies in the world, frequently reveals lymph
node, peritoneum, and liver metastases. Most of gastric cancer patients present with lymph …

Irritable bowel syndrome (IBS) is traditionally defined as a functional disorder since it lacks
demonstrable pathological abnormalities. However, in recent years, low grade inflammatory …

The peptide substance P (SP) and the cytokine tumor necrosis factor (TNF) have been
implicated in inflammatory processes. Mast cells are recognized as important in …

Irritable bowel syndrome (IBS), the most common functional gastrointestinal disorder
referred to gastroenterologists, affects 7–10% of the general population worldwide. The lack …

Mast cells may be regarded as prototypes of innate immune cells that can be controlled by
neuronal mediators. Their activation has been implicated in many types of neuro …