Macro‐and microvascular endothelial dysfunction in diabetes: 糖尿病诱导的内皮细胞功能损伤

Y Shi, PM Vanhoutte - Journal of diabetes, 2017 - Wiley Online Library
血管内皮细胞和内皮细胞释放的活性因子是调控血管舒张功能的重要因素. 糖尿病是慢性心血管
疾病的高危因素之一. 目前认为高糖和糖尿病引起的内皮细胞功能障碍是造成血管功能改变 …

The therapeutic potential of curcumin: A review of clinical trials

B Salehi, Z Stojanović-Radić, J Matejić… - European journal of …, 2019 - Elsevier
Curcuma longa L., its derived extracts and even its major compound curcumin has a long
history of use and doubtless effectiveness, reported through increasingly detailed in vitro, ex …

Curcumin, the golden nutraceutical: multitargeting for multiple chronic diseases

AB Kunnumakkara, D Bordoloi… - British journal of …, 2017 - Wiley Online Library
Curcumin, a yellow pigment in the Indian spice Turmeric (Curcuma longa), which is
chemically known as diferuloylmethane, was first isolated exactly two centuries ago in 1815 …

Cellular and molecular mechanisms of curcumin in prevention and treatment of disease

SS Patel, A Acharya, RS Ray, R Agrawal… - Critical reviews in …, 2020 - Taylor & Francis
Curcumin is a naturally occurring polyphenolic compound present in rhizome of Curcuma
longa belonging to the family zingiberaceae. Growing experimental evidence revealed that …

Role of turmeric and curcumin in prevention and treatment of chronic diseases: Lessons learned from clinical trials

AB Kunnumakkara, M Hegde, D Parama… - ACS Pharmacology & …, 2023 - ACS Publications
Turmeric (Curcuma longa) has been used for thousands of years for the prevention and
treatment of various chronic diseases. Curcumin is just one of> 200 ingredients in turmeric …

Pharmaceutical strategies of improving oral systemic bioavailability of curcumin for clinical application

Z Ma, N Wang, H He, X Tang - Journal of Controlled Release, 2019 - Elsevier
Curcumin (Cur), a natural compound from Curcuma longa Linn, has various of
pharmacological activities such as anti-cancer, anti-inflammatory, anti-oxidant, anti …

Curcumin: an inflammasome silencer

S Hasanzadeh, MI Read, AR Bland, M Majeed… - Pharmacological …, 2020 - Elsevier
Curcumin is the major bioactive polyphenolic ingredient of turmeric. Increasing evidence
indicates that the health benefits of curcumin are mediated through its anti-inflammatory and …

Antioxidant and anti-inflammatory effects of curcumin/turmeric supplementation in adults: A GRADE-assessed systematic review and dose–response meta-analysis of …

MJ Dehzad, H Ghalandari, M Nouri, M Askarpour - Cytokine, 2023 - Elsevier
Turmeric and its prominent bioactive compound, curcumin, have been the subject of many
investigations with regard to their impact on inflammatory and oxidative balance in the body …

Diabetic nephropathy–complications and treatment

AKH Lim - International journal of nephrology and renovascular …, 2014 - Taylor & Francis
Diabetic nephropathy is a significant cause of chronic kidney disease and end-stage renal
failure globally. Much research has been conducted in both basic science and clinical …

Mechanisms of diabetic complications

JM Forbes, ME Cooper - Physiological reviews, 2013 - journals.physiology.org
It is increasingly apparent that not only is a cure for the current worldwide diabetes epidemic
required, but also for its major complications, affecting both small and large blood vessels …