BDNF: a key factor with multipotent impact on brain signaling and synaptic plasticity
P Kowiański, G Lietzau, E Czuba, M Waśkow… - Cellular and molecular …, 2018 - Springer
Brain-derived neurotrophic factor (BDNF) is one of the most widely distributed and
extensively studied neurotrophins in the mammalian brain. Among its prominent functions …
extensively studied neurotrophins in the mammalian brain. Among its prominent functions …
BDNF and hippocampal synaptic plasticity
G Leal, CR Bramham, CB Duarte - Vitamins and hormones, 2017 - Elsevier
Brain-derived neurotrophic factor (BDNF) belongs to a family of small secreted proteins that
also include nerve growth factor, neurotrophin 3, and neurotrophin 4. BDNF stands out …
also include nerve growth factor, neurotrophin 3, and neurotrophin 4. BDNF stands out …
Human umbilical cord plasma proteins revitalize hippocampal function in aged mice
JM Castellano, KI Mosher, RJ Abbey, AA McBride… - Nature, 2017 - nature.com
Ageing drives changes in neuronal and cognitive function, the decline of which is a major
feature of many neurological disorders. The hippocampus, a brain region subserving roles …
feature of many neurological disorders. The hippocampus, a brain region subserving roles …
BDNF and synaptic plasticity, cognitive function, and dysfunction
B Lu, G Nagappan, Y Lu - Neurotrophic factors, 2014 - Springer
Among all neurotrophins, brain-derived neurotrophic factor (BDNF) stands out for its high
level of expression in the brain and its potent effects on synapses. It is now widely accepted …
level of expression in the brain and its potent effects on synapses. It is now widely accepted …
Neurotrophin regulation of neural circuit development and function
H Park, M Poo - Nature Reviews Neuroscience, 2013 - nature.com
Brain-derived neurotrophic factor (BDNF)—a member of a small family of secreted proteins
that includes nerve growth factor, neurotrophin 3 and neurotrophin 4—has emerged as a …
that includes nerve growth factor, neurotrophin 3 and neurotrophin 4—has emerged as a …
Neurobiology of local and intercellular BDNF signaling
M Sasi, B Vignoli, M Canossa, R Blum - Pflügers Archiv-European Journal …, 2017 - Springer
Brain-derived neurotrophic factor (BDNF) is a member of the neurotrophin family of secreted
proteins. Signaling cascades induced by BDNF and its receptor, the receptor tyrosine kinase …
proteins. Signaling cascades induced by BDNF and its receptor, the receptor tyrosine kinase …
The physiology of regulated BDNF release
T Brigadski, V Leßmann - Cell and Tissue Research, 2020 - Springer
The neurotrophic factor BDNF is an important regulator for the development of brain circuits,
for synaptic and neuronal network plasticity, as well as for neuroregeneration and …
for synaptic and neuronal network plasticity, as well as for neuroregeneration and …
Sublime microglia: expanding roles for the guardians of the CNS
Recent findings challenge the concept that microglia solely function in disease states in the
central nervous system (CNS). Rather than simply reacting to CNS injury, infection, or …
central nervous system (CNS). Rather than simply reacting to CNS injury, infection, or …
BDNF-based synaptic repair as a disease-modifying strategy for neurodegenerative diseases
B Lu, G Nagappan, X Guan, PJ Nathan… - Nature Reviews …, 2013 - nature.com
Increasing evidence suggests that synaptic dysfunction is a key pathophysiological hallmark
in neurodegenerative disorders, including Alzheimer's disease. Understanding the role of …
in neurodegenerative disorders, including Alzheimer's disease. Understanding the role of …
BDNF-induced local protein synthesis and synaptic plasticity
G Leal, D Comprido, CB Duarte - Neuropharmacology, 2014 - Elsevier
Brain-derived neurotrophic factor (BDNF) is an important regulator of synaptic transmission
and long-term potentiation (LTP) in the hippocampus and in other brain regions, playing a …
and long-term potentiation (LTP) in the hippocampus and in other brain regions, playing a …