The global epidemic of drug-resistant tuberculosis is a catastrophic example of how
antimicrobial resistance is undermining the public health gains made possible by …

Drug resistance diagnostics that rely on the detection of resistance-related mutations could
expedite patient care and TB eradication. We perform minimum inhibitory concentration …

Antibiotic resistance is one of the most serious public health problems. Among bacterial
resistance, β-lactam antibiotic resistance is the most prevailing and threatening area …

China, with the third largest share of global tuberculosis cases, faces a substantial challenge
in its healthcare system as a result of the high burden of multidrug-resistant and rifampicin …

Nucleases are strictly regulated and often localized in the cell to avoid the uncontrolled
degradation of DNA and RNA. Here, a new type of nuclease complex, composed of RecJ3 …

Background Pan-genomic studies aim, for instance, at defining the core, dispensable and
unique genes within a species. A pan-genomics study for vaccine design tries to assess the …

Drug resistance is threatening attempts at tuberculosis epidemic control. Molecular
diagnostics for drug resistance that rely on the detection of resistance-related mutations …

У роботі розглядаються питання узагальнення відомих літературних джерел за останні
п'ять років стосовно біологічних властивостей 3-тіо-та 3-тіо-4-амінопохідних 1, 2, 4 …

The evolution of resistance to one antimicrobial can result in enhanced sensitivity to another,
known as “collateral sensitivity.” This underexplored phenomenon opens new therapeutic …

ABSTRACT β-Lactamases are the main cause of β-lactam resistance in many pathogenic
bacteria. To elucidate the relationships of β-lactamases in soil-dwelling Gram-positive β …