Discovering and understanding oncogenic gene fusions through data intensive computational approaches
NS Latysheva, MM Babu - Nucleic acids research, 2016 - academic.oup.com
Although gene fusions have been recognized as important drivers of cancer for decades,
our understanding of the prevalence and function of gene fusions has been revolutionized …
our understanding of the prevalence and function of gene fusions has been revolutionized …
Evaluation of de novo transcriptome assemblies from RNA-Seq data
B Li, N Fillmore, Y Bai, M Collins, JA Thomson… - Genome biology, 2014 - Springer
De novo RNA-Seq assembly facilitates the study of transcriptomes for species without
sequenced genomes, but it is challenging to select the most accurate assembly in this …
sequenced genomes, but it is challenging to select the most accurate assembly in this …
Extensive differences in gene expression between symbiotic and aposymbiotic cnidarians
EM Lehnert, ME Mouchka, MS Burriesci… - G3: Genes …, 2014 - academic.oup.com
Coral reefs provide habitats for a disproportionate number of marine species relative to the
small area of the oceans that they occupy. The mutualism between the cnidarian animal …
small area of the oceans that they occupy. The mutualism between the cnidarian animal …
Detecting and targetting oncogenic fusion proteins in the genomic era
The advent of widespread cancer genome sequencing has accelerated our understanding
of the molecular aberrations underlying malignant disease at an unprecedented rate …
of the molecular aberrations underlying malignant disease at an unprecedented rate …
Benchmark analysis of algorithms for determining and quantifying full-length mRNA splice forms from RNA-seq data
Motivation: Because of the advantages of RNA sequencing (RNA-Seq) over microarrays, it is
gaining widespread popularity for highly parallel gene expression analysis. For example …
gaining widespread popularity for highly parallel gene expression analysis. For example …
Comparative transcriptome analysis reveals molecular strategies of oriental river prawn Macrobrachium nipponense in response to acute and chronic nitrite stress
Macrobrachium nipponense is an economically and nutritionally important species
threatened by ambient superfluous nitrite. De novo RNA-Seq was used to explore the …
threatened by ambient superfluous nitrite. De novo RNA-Seq was used to explore the …
Transcriptomic Analysis of Petunia hybrida in Response to Salt Stress Using High Throughput RNA Sequencing
Salinity and drought stress are the primary cause of crop losses worldwide. In sodic saline
soils sodium chloride (NaCl) disrupts normal plant growth and development. The complex …
soils sodium chloride (NaCl) disrupts normal plant growth and development. The complex …
Neofunctionalization of zona pellucida proteins enhances freeze-prevention in the eggs of Antarctic notothenioids
The mechanisms by which the eggs of the Antarctic notothenioid fishes avoid freezing are
not fully understood. Zona pellucida proteins (ZPs) are constituents of the chorion which …
not fully understood. Zona pellucida proteins (ZPs) are constituents of the chorion which …
Planarian cholinesterase: molecular and functional characterization of an evolutionarily ancient enzyme to study organophosphorus pesticide toxicity
The asexual freshwater planarian Dugesia japonica has emerged as a medium-throughput
alternative animal model for neurotoxicology. We have previously shown that D. japonica …
alternative animal model for neurotoxicology. We have previously shown that D. japonica …
Transcriptome and physiological analysis of a lutein-producing alga Desmodesmus sp. reveals the molecular mechanisms for high lutein productivity
TJ Yeh, YF Tseng, YC Chen, Y Hsiao, PC Lee, TJ Chen… - Algal research, 2017 - Elsevier
A green alga Desmodesmus sp. JSC3 is a lutein producer that appears high in lutein
production in batch culture under 200 μmol· m− 2· s− 1 condition using 1 g∙ L− 1 sodium …
production in batch culture under 200 μmol· m− 2· s− 1 condition using 1 g∙ L− 1 sodium …