Heparan sulfate proteoglycans and viral attachment: true receptors or adaptation bias?

V Cagno, ED Tseligka, ST Jones, C Tapparel - Viruses, 2019 - mdpi.com
Heparan sulfate proteoglycans (HSPG) are composed of unbranched, negatively charged
heparan sulfate (HS) polysaccharides attached to a variety of cell surface or extracellular …

Virology, epidemiology, pathogenesis, and control of enterovirus 71

T Solomon, P Lewthwaite, D Perera… - The Lancet infectious …, 2010 - thelancet.com
First isolated in California, USA, in 1969, enterovirus 71 (EV71) is a major public health
issue across the Asia-Pacific region and beyond. The virus, which is closely related to …

[PDF][PDF] 深圳237 例手足口病肠道病毒血清型基因及临床特征

张寿斌, 廖华, 黄呈辉, 谭庆瑜, 张炜灵, 黄艳, 陈侃… - 2008 - zgddek.com
目的了解该地区手足口病临床和流行病学特征, 明确其肠道病毒血清型分布.
方法分别在肠道病毒基因组5! 端非编码区, cAV16 和EV71VP1 区设计通用引物和特异性引物 …

2008 年中国手足口病流行特征分析

王琦, 王子军 - 疾病监测, 2010 - jbjc.org
目的分析2008 年全国手足口病的流行特征, 以了解流行现状, 探讨流行规律,
为制定有效的防控策略提供依据. 方法采用描述性流行病学方法对国家疾病监测信息报告管理 …

Hand, foot, and mouth disease in China, 2008–12: an epidemiological study

W Xing, Q Liao, C Viboud, J Zhang, J Sun… - The Lancet infectious …, 2014 - thelancet.com
Background Hand, foot, and mouth disease is a common childhood illness caused by
enteroviruses. Increasingly, the disease has a substantial burden throughout east and …

Efficacy, safety, and immunogenicity of an enterovirus 71 vaccine in China

F Zhu, W Xu, J Xia, Z Liang, Y Liu… - … England Journal of …, 2014 - Mass Medical Soc
Background Enterovirus 71 (EV71) is one of the major causative agents of outbreaks of
hand, foot, and mouth disease or herpangina worldwide. This phase 3 trial was designed to …

Clinical features, diagnosis, and management of enterovirus 71

MH Ooi, SC Wong, P Lewthwaite, MJ Cardosa… - The Lancet …, 2010 - thelancet.com
Although poliomyelitis has been mostly eradicated worldwide, large outbreaks of the related
enterovirus 71 have been seen in Asia-Pacific countries in the past 10 years. This virus …

Efficacy, safety, and immunology of an inactivated alum-adjuvant enterovirus 71 vaccine in children in China: a multicentre, randomised, double-blind, placebo …

FC Zhu, FY Meng, JX Li, XL Li, QY Mao, H Tao… - The Lancet, 2013 - thelancet.com
Background A vaccine for enterovirus 71 (EV71) is needed to address the high burden of
disease associated with infection. We assessed the efficacy, safety, immunogenicity …

The history of enterovirus A71 outbreaks and molecular epidemiology in the Asia-Pacific region

J Puenpa, N Wanlapakorn, S Vongpunsawad… - Journal of biomedical …, 2019 - Springer
Abstract Enterovirus A71 (EV-A71) is one of the common causative pathogens for hand foot
and mouth disease (HFMD) affecting young children. HFMD outbreak can result in a …

[引用][C] 手足口病流行病学研究进展

孙军玲, 张静 - 中华流行病学杂志, 2009