abstract Biocatalysts are creating increased interest among researchers due to their unique
properties. Several enzymes are efficiently produced by microorganisms. However, the use …

Esterases are a large family of enzymes with wide applications in the industry. However, all
esterases originated from natural sources, limiting their use in harsh environments or newly …

This chapter discusses the recent status of protein/enzyme engineering related to
improvement activity, with an emphasis on the implications for industrial biotechnology …

Computational methods have been developed to redesign proteins so that they can perform
novel functions such as the catalysis of nonnatural reactions. Active sites are constructed …

Increasing global population, environmental pressures, depletion of many resources at a
rapid pace and drastic climate changes are some of the global challenges that are …

Enzymes are biological catalysts ubiquitous in all life forms, allowing chemical reactions to
proceed at rates otherwise unachievable. Although the indirect use of enzymes may date …

Presented here are a trio of computational projects that, on the surface, have seemingly little
in common:(1) proposing a new bioactive conformation of epothilone;(2) creating an amyloid …