Essential oils and isolated terpenes in nanosystems designed for topical administration: A review

SP de Matos, HF Teixeira, ÁAN De Lima… - Biomolecules, 2019 - mdpi.com
Essential oils are natural products with a complex composition. Terpenes are the most
common class of chemical compounds present in essential oils. Terpenes and the essential …

The expanded role of chitosan in localized antimicrobial therapy

LM Hemmingsen, N Škalko-Basnet, MW Jøraholmen - Marine Drugs, 2021 - mdpi.com
Chitosan is one of the most studied natural origin polymers for biomedical applications. This
review focuses on the potential of chitosan in localized antimicrobial therapy to address the …

Bilosomes as promising nanovesicular carriers for improved transdermal delivery: construction, in vitro optimization, ex vivo permeation and in vivo evaluation

S Ahmed, MA Kassem, S Sayed - International Journal of …, 2020 - Taylor & Francis
Purpose The goal of this research was to enhance the transdermal delivery of lornoxicam
(LX), using nanovesicular carriers composed of the bile salt sodium deoxycholate (SDC) …

Transdermal application of diacerin loaded-terpene enriched invasomes: an approach to augment anti-edema and nociception inhibition activity

S Ahmed, MM Farag, MA Sadek… - Journal of Liposome …, 2024 - Taylor & Francis
This study aimed to formulate diacerein loaded terpene-enriched invasomes (DCN-TINV) to
fulfill a fruitful management of osteoarthritis. A 23 factorial design was adopted, including A …

Luteolin-loaded elastic liposomes for transdermal delivery to control breast cancer: In vitro and ex vivo evaluations

MA Altamimi, A Hussain, M AlRajhi, S Alshehri… - Pharmaceuticals, 2021 - mdpi.com
The study aimed to prepare and optimize luteolin (LUT)-loaded transdermal elastic
liposomes (LEL1-LEL12), followed by in vitro and ex vivo evaluations of their ability to …

Paeonol-loaded ethosomes as transdermal delivery carriers: design, preparation and evaluation

H Ma, D Guo, Y Fan, J Wang, J Cheng, X Zhang - Molecules, 2018 - mdpi.com
Paeonol exhibits a wide range of pharmacological activities, such as anti-inflammatory,
antidiabetic as well as pain-relieving activities. However, its intrinsic properties, such as low …

Therapeutic potential of cationic bilosomes in the treatment of carrageenan-induced rat arthritis via fluticasone propionate gel

AH AbuBakr, HAFM Hassan, A Abdalla… - International Journal of …, 2023 - Elsevier
Arthritis is a debilitating disease that affects the patient's mobility and quality of life. This
study focused on the development and optimization of a cationic nanosized bilosomal …

Enhanced transdermal delivery of ondansetron using nanovesicular systems: fabrication, characterization, optimization and ex-vivo permeation study-Box-Cox …

BA Habib, S Sayed, GM Elsayed - European journal of pharmaceutical …, 2018 - Elsevier
This study aimed to formulate suitable nanovesicles (NVs) for transdermal delivery of
Ondansetron. It also illustrated a practical example for the importance of Box-Cox …

Fluidized spanlastics for intranasal brain delivery of lacosamide aiming to control Status Epilepticus: Design, Characterization, Ex-vivo permeation, Radioiodination …

ME Sayyed, S Hatem - Journal of Drug Delivery Science and Technology, 2024 - Elsevier
Status Epilepticus (SE) is a neurological condition characterized by anomalous brain
activity, causing repetitive seizures lasting for more than 5 min or periods of unusual …

Nano-vesicular systems for melanocytes targeting and melasma treatment: In-vitro characterization, ex-vivo skin retention, and preliminary clinical appraisal

S Hatem, AO Kamel, SA Elkheshen, M Nasr… - International Journal of …, 2024 - Elsevier
Melasma represents an acquired melanogenesis disorder resulting in skin's
hyperpigmentation effect. Although several approaches are adopted for melasma treatment …