Human cytomegalovirus (HCMV) represents a prototypic pathogenic member of the β‐
subgroup of the herpesvirus family. A range of HCMV features like its lytic replication in …

Natural killer (NK) cells play a significant role in immune tolerance and immune surveillance.
Killer immunoglobin-like receptors (KIRs), which recognize human leukocyte antigen (HLA) …

Human natural killer (NK) cells are functionally regulated by killer cell immunoglobulin-like
receptors (KIRs) and their interactions with HLA class I molecules. As KIR expression in a …

The association between cytomegalovirus (CMV) reactivation and relapse was evaluated in
a large cohort of patients with acute myeloid leukemia (AML)(n= 761), acute lymphoblastic …

Human cytomegalovirus (HCMV) infection is the most common cause of congenital viral
infections and a major source of morbidity and mortality after organ transplantation. NK cells …

Killer cell immunoglobulin‐like receptors (KIR s) on natural killer (NK) cells are crucially
involved in the control of cancer development and virus infection by probing cells for proper …

The immune system of an individual human is determined by heritable traits and a
continuous process of adaptation to a broad variety of extrinsic, non-heritable factors such …

Interactions between HLA class I molecules and killer-cell immunoglobulin-like receptors
(KIR) control natural killer cell (NK) functions in immunity and reproduction. Encoded by …

Natural killer (NK) cells represent a critical defense against viral infections and cancers. NK
cells require integration of activating and inhibitory NK cell receptors to detect target cells …

The interaction of inhibitory killer cell Ig-like receptors (KIRs) with human leukocyte antigen
(HLA) class I molecules has been characterized in detail. By contrast, activating members of …