This paper is a logical continuation of the theoretical survey of the CH⋯ O/N specific contacts
in the nucleobase pairs using a wide arsenal of the modern methods, which was initiated in …

DNA glycosylases that remove alkylated and deaminated purine nucleobases are essential
DNA repair enzymes that protect the genome, and at the same time confound cancer …

Polyplexes composed of polyethyleneimine (PEI) and DNA or siRNA have attracted great
attention for their use in gene therapy. Although many physicochemical characteristics of …

Hydration plays a key role in the structure-specific stabilization of biomolecules such as
nucleic acids. The hydration patterns of biased DNA sequences in the genome, such as GC …

Deazapurine nucleosides such as 3-deazaadenosine (c3A) are crucial for atomic
mutagenesis studies of functional RNAs. They were the key for our current mechanistic …

Transport of positive charge or holes in DNA occurs via a thermally activated multi-step
hopping mechanism. The fastest hopping rates reported to date are those for repeating poly …

The spiroiminodihydantoins (Sp) are highly mutagenic oxidation products of guanine and 8-
oxo-7, 8-dihydroguanine in DNA. The Sp lesions have recently been detected in the liver …

Lucidin is a genotoxic and mutagenic hydroxyanthraquinone metabolite, which originates
from the roots of Rubia tinctorum L.(madder root). It reacts with exocyclic amino groups of …

The DNA sequence preferences of nearly all sequence specific DNA binding proteins are
influenced by the identities of bases that are not directly contacted by protein. Discrimination …

Conspectus DNA in its simplest form is an ensemble of nucleic acids, water, and ions, and
the conformation of DNA is dependent on the relative proportions of all three components …