Radiolabelling of nanomaterials for medical imaging and therapy

J Pellico, PJ Gawne, RTM de Rosales - Chemical Society Reviews, 2021 - pubs.rsc.org
Nanomaterials offer unique physical, chemical and biological properties of interest for
medical imaging and therapy. Over the last two decades, there has been an increasing effort …

Assessing the interactions between radiotherapy and antitumour immunity

C Grassberger, SG Ellsworth, MQ Wilks… - Nature reviews Clinical …, 2019 - nature.com
Immunotherapy, specifically the introduction of immune checkpoint inhibitors, has
transformed the treatment of cancer, enabling long-term tumour control even in individuals …

Nanoparticle radio-enhancement: principles, progress and application to cancer treatment

Z Kuncic, S Lacombe - Physics in Medicine & Biology, 2018 - iopscience.iop.org
Enhancement of radiation effects by high-atomic number nanoparticles (NPs) has been
increasingly studied for its potential to improve radiotherapeutic efficacy. The underlying …

Radiolabeling nanomaterials for multimodality imaging: New insights into nuclear medicine and cancer diagnosis

J Ge, Q Zhang, J Zeng, Z Gu, M Gao - Biomaterials, 2020 - Elsevier
Nuclear medicine imaging has been developed as a powerful diagnostic approach for
cancers by detecting gamma rays directly or indirectly from radionuclides to construct …

In vivo imaging of human neuroinflammation

DS Albrecht, C Granziera, JM Hooker… - ACS chemical …, 2016 - ACS Publications
Neuroinflammation is implicated in the pathophysiology of a growing number of human
disorders, including multiple sclerosis, chronic pain, traumatic brain injury, and amyotrophic …

Nanoparticles for MRI-guided radiation therapy: A review

L Smith, HL Byrne, D Waddington, Z Kuncic - Cancer Nanotechnology, 2022 - Springer
The development of nanoparticle agents for MRI-guided radiotherapy is growing at an
increasing pace, with clinical trials now underway and many pre-clinical evaluation studies …

Biodistribution and clearance of stable superparamagnetic maghemite iron oxide nanoparticles in mice following intraperitoneal administration

BTT Pham, EK Colvin, NTH Pham, BJ Kim… - International journal of …, 2018 - mdpi.com
Nanomedicine is an emerging field with great potential in disease theranostics. We
generated sterically stabilized superparamagnetic iron oxide nanoparticles (s-SPIONs) with …

Imaging of anticancer drug action in single cells

MA Miller, R Weissleder - Nature Reviews Cancer, 2017 - nature.com
Imaging is widely used in anticancer drug development, typically for whole-body tracking of
labelled drugs to different organs or to assess drug efficacy through volumetric …

Multimodal nanoparticle imaging agents: design and applications

BP Burke, C Cawthorne… - … Transactions of the …, 2017 - royalsocietypublishing.org
Molecular imaging, where the location of molecules or nanoscale constructs can be tracked
in the body to report on disease or biochemical processes, is rapidly expanding to include …

[HTML][HTML] PET-MR and SPECT-MR multimodality probes: Development and challenges

CT Yang, KK Ghosh, P Padmanabhan, O Langer… - Theranostics, 2018 - ncbi.nlm.nih.gov
Positron emission tomography (PET)-magnetic resonance (MR) or single photon emission
computed tomography (SPECT)-MR hybrid imaging is being used in daily clinical practice …