Cord blood research, banking, and transplantation: achievements, challenges, and perspectives

H Mayani, JE Wagner, HE Broxmeyer - Bone marrow transplantation, 2020 - nature.com
The first hematopoietic transplant in which umbilical cord blood (UCB) was used as the
source of hematopoietic cells was performed in October 1988. Since then, significant …

[HTML][HTML] Optimal practices in unrelated donor cord blood transplantation for hematologic malignancies

JN Barker, J Kurtzberg, K Ballen, M Boo… - Biology of Blood and …, 2017 - Elsevier
Unrelated donor cord blood transplantation (CBT) results in disease-free survival
comparable to that of unrelated adult donor transplantation in patients with hematologic …

[HTML][HTML] Phase I/II trial of StemRegenin-1 expanded umbilical cord blood hematopoietic stem cells supports testing as a stand-alone graft

JE Wagner, CG Brunstein, AE Boitano, TE DeFor… - Cell stem cell, 2016 - cell.com
Clinical application of umbilical cord blood (UCB) as a source of hematopoietic stem cells for
transplantation is limited by low CD34+ cell dose, increased risk of graft failure, and slow …

[图书][B] Wintrobe's clinical hematology

MM Wintrobe - 2009 - books.google.com
Now available in a thoroughly revised Twelfth Edition, Wintrobe's Clinical Hematology
continues to be an industry leader with its ability to correlate basic science with the clinical …

Multiplexed genetic engineering of human hematopoietic stem and progenitor cells using CRISPR/Cas9 and AAV6

RO Bak, DP Dever, A Reinisch, D Cruz Hernandez… - Elife, 2017 - elifesciences.org
Precise and efficient manipulation of genes is crucial for understanding the molecular
mechanisms that govern human hematopoiesis and for developing novel therapies for …

Selectins and immune cells in acute myocardial infarction and post-infarction ventricular remodeling: pathophysiology and novel treatments

BR Weil, S Neelamegham - Frontiers in immunology, 2019 - frontiersin.org
The glycosciences aim to understand the impact of extracellular and intracellular
carbohydrate structures on biological function. These glycans primarily fall into three major …

[HTML][HTML] Advances in umbilical cord blood stem cell expansion and clinical translation

N Pineault, A Abu-Khader - Experimental hematology, 2015 - Elsevier
Umbilical cord blood (CB) is a rich source of hematopoietic stem cells (HSCs) with important
applications in allogeneic stem cell transplantation. However, the low numbers of …

Allogeneic hematopoietic cell transplantation; the current renaissance

EA Copelan, A Chojecki, HM Lazarus, BR Avalos - Blood Reviews, 2019 - Elsevier
Allogeneic hematopoietic cell transplantation (HCT) provides the best chance for cure for
many patients with malignant and nonmalignant hematologic disorders. Recent advances in …

Single-vs double-unit cord blood transplantation for children and young adults with acute leukemia or myelodysplastic syndrome

G Michel, C Galambrun, A Sirvent… - Blood, The Journal …, 2016 - ashpublications.org
Transplantation of 2 unrelated cord blood (UCB) units instead of 1 has been proposed to
increase the cell dose. We report a prospective randomized study, designed to compare …

Umbilical cord blood transplantation: connecting its origin to its future

G Sanchez-Petitto, K Rezvani, M Daher… - Stem cells …, 2023 - academic.oup.com
Transplantation of umbilical cord blood (UCB) is an attractive alternative source of
hematopoietic stem cells (HSCs). The unique properties of cord blood and its distinct …