Cytokine Storm Cytokine storm, a life-threatening disorder involving cytokine elevations and
immune-cell hyperactivation, has various causes and is characterized by constitutional …

A subset of patients with severe COVID-19 develop profound inflammation and multi-organ
dysfunction consistent with a “Cytokine Storm Syndrome”(CSS). In this review we compare …

Castleman disease (CD), a heterogeneous group of disorders that share morphological
features, is divided into unicentric CD and multicentric CD (MCD) according to the clinical …

Castleman disease (CD) is a rare lymphoproliferative disorder. Among subtypes of CD,
idiopathic multicentric CD-not otherwise specified (iMCD-NOS) has a poor prognosis and its …

Still's disease is a severe inflammatory syndrome characterized by fever, skin rash and
arthritis affecting children and adults. Patients with Still's disease may also develop …

Idiopathic multicentric Castleman disease (iMCD) is a rare and poorly-understood cytokine
storm-driven inflammatory disorder. Interleukin-6 (IL-6) is a known disease driver in some …

The mTOR pathway plays a central role in many cellular processes, such as cellular growth,
protein synthesis, glucose, and lipid metabolism. Aberrant regulation of mTOR is a hallmark …

Idiopathic multicentric Castleman disease (iMCD) is a poorly understood hematologic
disorder involving cytokine-induced polyclonal lymphoproliferation, systemic inflammation …

Objective This study was initiated to evaluate mammalian target of rapamycin (mTOR)
activation in renal tissue of LN patients. Methods This retrospective study included 187 LN …

Idiopathic multicentric Castleman disease (iMCD) is a type of Castleman disease that is not
related to KSHV/HHV8 infection. Currently, iMCD is classified into iMCD-TAFRO …