Severe ocular surface disease can result in limbal stem cell deficiency (LSCD), a condition
leading to decreased visual acuity, photophobia, and ocular pain. To restore the ocular …

Corneal wound healing is a complex process that occurs in response to various injuries and
commonly used refractive surgery. It is a significant clinical problem, which may lead to …

Purpose: Ex vivo cultured limbal epithelial transplantation (CLET) with amniotic membrane
(AM) as the substrate is a relatively new type of surgical therapy in treating limbal stem cell …

Corneal blindness affects over 10 million people worldwide and current treatment strategies
often involve replacement of the defective layer with healthy tissue. Due to a worldwide …

Purpose This systematic review (SR) assessed the efficacy, safety and cost-effectiveness of
cell-based therapy to manage limbal stem cell deficiency (LSCD), a sight-threatening …

Purpose To overcome problems and delays of the preparation of autologous serum eye
drops, a production line of ABO‐specific allogeneic serum eye drops from male blood …

Corneal integrity is essential for visual function. Transplantation remains the most common
treatment option for advanced corneal diseases. A global donor material shortage requires a …

Ex vivo cultivated limbal stem cell transplantation is a promising technique for the treatment
of limbal stem cell deficiency. While the results of the clinical trials have been extensively …

Limbal stem cell deficiency (LSCD) can result from a variety of corneal disorders, including
chemical and thermal burns, infections, and autoimmune diseases. The symptoms of LSCD …

PURPOSE Taking into consideration prior human experience with treating limbal stem cell
deficiency (LSCD) with cultivated limbal epithelial cells (CLEC) from other countries, we …