Clinical updates on phantom limb pain

J Erlenwein, M Diers, J Ernst, F Schulz, F Petzke - Pain reports, 2021 - journals.lww.com
Methods: This review aims to provide an interdisciplinary overview of recent evidence-based
and clinical knowledge. Results: The scientific evidence for best practice is weak and …

Neurobiology of brain oscillations in acute and chronic pain

LL Tan, MJ Oswald, R Kuner - Trends in neurosciences, 2021 - cell.com
Pain is a complex perceptual phenomenon. Coordinated activity among local and distant
brain networks is a central element of the neural underpinnings of pain. Brain oscillatory …

The (un) conscious mouse as a model for human brain functions: key principles of anesthesia and their impact on translational neuroimaging

HM Reimann, T Niendorf - Frontiers in systems neuroscience, 2020 - frontiersin.org
In recent years, technical and procedural advances have brought functional magnetic
resonance imaging (fMRI) to the field of murine neuroscience. Due to its unique capacity to …

The dissociative and analgesic properties of ketamine are independent

J Gitlin, S Chamadia, JJ Locascio, BR Ethridge… - …, 2020 - pmc.ncbi.nlm.nih.gov
Background Ketamine is a dissociative anesthetic with analgesic properties. Ketamine's
analgesic properties have been suggested to result from its dissociative properties. To our …

Brain complexities and anesthesia: Their meaning and measurement

D Li, MS Fabus, JW Sleigh - Anesthesiology, 2022 - ingentaconnect.com
A complex system is often associated with emergence of new phenomena from the
interactions between the system's components. General anesthesia reduces brain …

Intrinsic phase–amplitude coupling on multiple spatial scales during the loss and recovery of consciousness

K Dong, D Zhang, Q Wei, G Wang, F Huang… - Computers in Biology …, 2022 - Elsevier
Background: Recent studies have demonstrated that changes in brain information
processing during anesthetic-induced loss of consciousness (LOC) might be influenced by …

A pharmacokinetic and pharmacodynamic study of oral dexmedetomidine

S Chamadia, JC Pedemonte, LE Hobbs… - …, 2020 - pmc.ncbi.nlm.nih.gov
Background: Dexmedetomidine is only approved for use in humans as an intravenous
medication. An oral formulation may broaden the use and benefits of dexmedetomidine to …

Cortical complexity and connectivity during isoflurane-induced general anesthesia: a rat study

Z Wang, F Zhang, L Yue, L Hu, X Li… - Journal of Neural …, 2022 - iopscience.iop.org
Objective. The investigation of neurophysiologic mechanisms of anesthetic drug-induced
loss of consciousness (LOC) by using the entropy, complexity, and information integration …

[HTML][HTML] Progress of brain network studies on anesthesia and consciousness: framework and clinical applications

J Liu, K Dong, Y Sun, I Kakkos, F Huang, G Wang, P Qi… - Engineering, 2023 - Elsevier
Although the relationship between anesthesia and consciousness has been investigated for
decades, our understanding of the underlying neural mechanisms of anesthesia and …

[HTML][HTML] Age-dependent cross frequency coupling features from children to adults during general anesthesia

Z Liang, N Ren, X Wen, H Li, H Guo, Y Ma, Z Li, X Li - Neuroimage, 2021 - Elsevier
Background The frequency coupling characteristics in electroencephalogram (EEG) induced
by anesthetics have been well studied in adults, but the investigation of the age-dependent …