The CD4+ T cell response to human cytomegalovirus in healthy and immunocompromised people
While CD8+ T cells specific for human cytomegalovirus (HCMV) have been extensively
studied in both healthy HCMV seropositive carriers and patients undergoing …
studied in both healthy HCMV seropositive carriers and patients undergoing …
Generation, maintenance and tissue distribution of T cell responses to human cytomegalovirus in lytic and latent infection
SE Jackson, GX Sedikides, G Okecha… - Medical Microbiology and …, 2019 - Springer
Understanding how the T cell memory response directed towards human cytomegalovirus
(HCMV) develops and changes over time while the virus persists is important. Whilst HCMV …
(HCMV) develops and changes over time while the virus persists is important. Whilst HCMV …
Transcriptome-based analysis of human peripheral blood reveals regulators of immune response in different viral infections
SM Ivanov, OA Tarasova, VV Poroikov - Frontiers in Immunology, 2023 - frontiersin.org
Introduction There are difficulties in creating direct antiviral drugs for all viruses, including
new, suddenly arising infections, such as COVID-19. Therefore, pathogenesis-directed …
new, suddenly arising infections, such as COVID-19. Therefore, pathogenesis-directed …
[HTML][HTML] Maternal natural killer cells at the intersection between reproduction and mucosal immunity
EV Shmeleva, F Colucci - Mucosal Immunology, 2021 - Elsevier
Many maternal immune cells populate the decidua, which is the mucosal lining of the uterus
transformed during pregnancy. Here, abundant natural killer (NK) cells and macrophages …
transformed during pregnancy. Here, abundant natural killer (NK) cells and macrophages …
Shared molecular signatures across neurodegenerative diseases and herpes virus infections highlights potential mechanisms for maladaptive innate immune …
AC Costa Sa, H Madsen, JR Brown - Scientific Reports, 2019 - nature.com
Growing evidence suggests that peripheral factors to the brain driving neuro-inflammation
could affect Alzheimer's Disease (AD) and Parkinson's Disease (PD) severity. Herpes …
could affect Alzheimer's Disease (AD) and Parkinson's Disease (PD) severity. Herpes …
Cell type-specific biogenesis of novel vesicles containing viral products in human cytomegalovirus infection
Human cytomegalovirus (HCMV), while highly restricted for the human species, infects a
diverse array of cell types in the host. Patterns of infection are dictated by the cell type …
diverse array of cell types in the host. Patterns of infection are dictated by the cell type …
[HTML][HTML] Systems immunology of transcriptional responses to viral infection identifies conserved antiviral pathways across macaques and humans
Viral pandemics and epidemics pose a significant global threat. While macaque models of
viral disease are routinely used, it remains unclear how conserved antiviral responses are …
viral disease are routinely used, it remains unclear how conserved antiviral responses are …
Immunotherapy with adoptive cytomegalovirus‐specific T cells transfer: Summarizing latest gene engineering techniques
M Mehdizadeh, S Karami… - Health science …, 2021 - Wiley Online Library
Cytomegalovirus (CMV) infection remains a major complication following allogeneic
hematopoietic stem cell transplantation (HSCT). T cell response plays a critical role in …
hematopoietic stem cell transplantation (HSCT). T cell response plays a critical role in …
CD1-restricted T cells during persistent virus infections:“sympathy for the devil”
G Schönrich, MJ Raftery - Frontiers in Immunology, 2018 - frontiersin.org
Some of the clinically most important viruses persist in the human host after acute infection.
In this situation, the host immune system and the viral pathogen attempt to establish an …
In this situation, the host immune system and the viral pathogen attempt to establish an …
Cytokine-mediated tissue injury in non-human primate models of viral infections
Viral infections trigger robust secretion of interferons and other antiviral cytokines by infected
and bystander cells, which in turn can tune the immune response and may lead to viral …
and bystander cells, which in turn can tune the immune response and may lead to viral …