Graph representation learning in biomedicine and healthcare

MM Li, K Huang, M Zitnik - Nature Biomedical Engineering, 2022 - nature.com
Networks—or graphs—are universal descriptors of systems of interacting elements. In
biomedicine and healthcare, they can represent, for example, molecular interactions …

Deep learning in systems medicine

H Wang, E Pujos-Guillot, B Comte… - Briefings in …, 2021 - academic.oup.com
Abstract Systems medicine (SM) has emerged as a powerful tool for studying the human
body at the systems level with the aim of improving our understanding, prevention and …

Exploring the genetic overlap between twelve psychiatric disorders

C Romero, J Werme, PR Jansen, J Gelernter… - Nature …, 2022 - nature.com
The widespread comorbidity among psychiatric disorders demonstrated in epidemiological
studies,,,–is mirrored by non-zero, positive genetic correlations from large-scale genetic …

A weighted patient network-based framework for predicting chronic diseases using graph neural networks

H Lu, S Uddin - Scientific reports, 2021 - nature.com
Chronic disease prediction is a critical task in healthcare. Existing studies fulfil this
requirement by employing machine learning techniques based on patient features, but they …

Machine learning applications in preventive healthcare: A systematic literature review on predictive analytics of disease comorbidity from multiple perspectives

XU Duo, XU Zeshui - Artificial Intelligence in Medicine, 2024 - Elsevier
Artificial intelligence is constantly revolutionizing biomedical research and healthcare
management. Disease comorbidity is a major threat to the quality of life for susceptible …

Patterns of comorbidity in hepatocellular carcinoma: a network perspective

XM Mu, W Wang, YY Jiang, J Feng - International Journal of …, 2020 - mdpi.com
Hepatocellular carcinoma (HCC) is a common and fatal cancer. People with HCC report
higher odds of comorbidity compared with people without HCC. To explore the association …

An explainable artificial intelligence approach for predicting cardiovascular outcomes using electronic health records

S Wesołowski, G Lemmon, EJ Hernandez… - PLOS digital …, 2022 - journals.plos.org
Understanding the conditionally-dependent clinical variables that drive cardiovascular
health outcomes is a major challenge for precision medicine. Here, we deploy a recently …

Comorbidity networks in cardiovascular diseases

HA Cruz-Ávila, M Vallejo, M Martínez-García… - Frontiers in …, 2020 - frontiersin.org
Background: Cardiovascular diseases are the leading causes of mortality worldwide. One
reason behind this lethality lies in the fact that often cardiovascular illnesses develop into …

[HTML][HTML] Comorbidity Patterns in Patients Newly Diagnosed With Colorectal Cancer: Network-Based Study

H Qiu, L Wang, L Zhou, X Wang - JMIR Public Health and …, 2023 - publichealth.jmir.org
Background Patients with colorectal cancer (CRC) often present with multiple comorbidities,
and many of these can affect treatment and survival. However, previous comorbidity studies …

The impact of untreated hearing loss on depression, anxiety, stress, and loneliness in tonal language-speaking older adults in China

X Fu, RH Eikelboom, B Liu, S Wang… - Frontiers in …, 2022 - frontiersin.org
Background Age-related hearing loss, mental health conditions, and loneliness commonly
affect older adults. This study aimed to determine whether untreated hearing loss is …