N-methyl-d-aspartate (NMDA) receptor dysfunction or dysregulation: the final common pathway on the road to schizophrenia?

JT Kantrowitz, DC Javitt - Brain research bulletin, 2010 - Elsevier
Schizophrenia is a severe mental disorder associated with a characteristic constellation of
symptoms and neurocognitive deficits. At present, etiological mechanisms remain relatively …

Cognitive training for impaired neural systems in neuropsychiatric illness

S Vinogradov, M Fisher… - …, 2012 - nature.com
Neuropsychiatric illnesses are associated with dysfunction in distributed prefrontal neural
systems that underlie perception, cognition, social interactions, emotion regulation, and …

Has an angel shown the way? Etiological and therapeutic implications of the PCP/NMDA model of schizophrenia

DC Javitt, SR Zukin, U Heresco-Levy… - Schizophrenia …, 2012 - academic.oup.com
Over the last 20 years, glutamatergic models of schizophrenia have become increasingly
accepted as etiopathological models of schizophrenia, based on the observation that …

[HTML][HTML] Schizophrenia as a self-disorder due to perceptual incoherence

L Postmes, HN Sno, S Goedhart, J Van Der Stel… - Schizophrenia …, 2014 - Elsevier
The aim of this review is to describe the potential relationship between multisensory
disintegration and self-disorders in schizophrenia spectrum disorders. Sensory processing …

Emotion recognition in individuals at clinical high-risk for schizophrenia

GP Amminger, MR Schäfer… - Schizophrenia …, 2012 - academic.oup.com
Problems in the perception of emotional material, in particular deficits in the recognition of
negative stimuli, have been demonstrated in schizophrenia including in first-episode …

Visual perception disturbances in schizophrenia: a unified model

SM Silverstein - … of schizophrenia: Molecules, brain systems, motivation …, 2016 - Springer
The purpose of this chapter is to demonstrate that the study of visual processing
abnormalities in schizophrenia offers a unifying perspective on the etiology, development …

Emotion recognition deficits as predictors of transition in individuals at clinical high risk for schizophrenia: a neurodevelopmental perspective

CM Corcoran, JG Keilp, J Kayser, C Klim… - Psychological …, 2015 - cambridge.org
Background. Schizophrenia is characterized by profound and disabling deficits in the ability
to recognize emotion in facial expression and tone of voice. Although these deficits are well …

Compressed sensorimotor-to-transmodal hierarchical organization in schizophrenia

D Dong, D Yao, Y Wang, SJ Hong, S Genon… - Psychological …, 2023 - cambridge.org
BackgroundSchizophrenia has been primarily conceptualized as a disorder of high-order
cognitive functions with deficits in executive brain regions. Yet due to the increasing reports …

Early sensory contributions to contextual encoding deficits in schizophrenia

EC Dias, PD Butler, MJ Hoptman… - Archives of general …, 2011 - jamanetwork.com
Context The AX version of the visual continuous performance task (AX-CPT) is widely used
for investigating visual working memory dysfunction in schizophrenia. Event-related …

Retinal layer abnormalities as biomarkers of schizophrenia

NN Samani, FA Proudlock, V Siram… - Schizophrenia …, 2018 - academic.oup.com
Objective Schizophrenia is associated with several brain deficits, as well as visual
processing deficits, but clinically useful biomarkers are elusive. We hypothesized that retinal …