Ferroptosis inhibitors: past, present and future

L Zhang, YL Luo, Y Xiang, XY Bai, RR Qiang… - Frontiers in …, 2024 - frontiersin.org
Ferroptosis is a non-apoptotic mode of programmed cell death characterized by iron
dependence and lipid peroxidation. Since the ferroptosis was proposed, researchers have …

Hinokitiol-iron complex is a ferroptosis inducer to inhibit triple-negative breast tumor growth

H Zhao, M Zhang, J Zhang, Z Sun, W Zhang, W Dong… - Cell & Bioscience, 2023 - Springer
Background Ferroptosis is a unique cell death, dependent on iron and phospholipid
peroxidation, involved in massive processes of physiopathology. Tremendous attention has …

Induction of ferroptosis: a new strategy for the control of bacterial infections

R Guo, X Fang, K Shang, J Wen, K Ding - Microbiological Research, 2024 - Elsevier
The continued rise of drug-resistant bacterial infections heightens a threat of a pandemic of
antimicrobial resistance to the global health. The urgency of infection control against …

Functionalized antibacterial peptide with DNA cleavage activity for enhanced bacterial disinfection

W Wang, P Li, Q Huang, Q Zhu, S He, W Bing… - Colloids and Surfaces B …, 2023 - Elsevier
Antibiotics are commonly used to treat bacterial infections, but the misuse and abuse of
antibiotics have given rise to a severe problem of the drug resistance of bacteria. Solving …

Bi 2 O 3 nanoparticles exhibit potent broad-spectrum antimicrobial activity and the ability to overcome Ag-, ciprofloxacin-and meropenem-resistance in P. aeruginosa …

BD Pant, BM Benin, N Abeydeera, MH Kim… - Biomaterials …, 2022 - pubs.rsc.org
Antimicrobial resistance is a persistent threat to global public health. In order to combat the
spread of pathogenic bacteria, numerous antimicrobial materials have been incorporated …

Harnessing the Dual Antimicrobial Mechanism of Action with Fe(8-Hydroxyquinoline)3 to Develop a Topical Ointment for Mupirocin-Resistant MRSA Infections

N Abeydeera, BM Benin, K Mudarmah, BD Pant… - Antibiotics, 2023 - mdpi.com
8-Hydroxyquinoline (8-hq) exhibits potent antimicrobial activity against Staphylococcus
aureus (SA) bacteria with MIC= 16.0–32.0 µM owing to its ability to chelate metal ions such …

Lipophilic Fe (III)-Complex with Potent Broad-Spectrum Anticancer Activity and Ability to Overcome Pt Resistance in A2780cis Cancer Cells

N Abeydeera, M Stilgenbauer, BD Pant, K Mudarmah… - Molecules, 2023 - mdpi.com
Although iron is essential for all forms of life, it is also potentially toxic to cells as the
increased and unregulated iron uptake can catalyze the Fenton reaction to produce reactive …

Transferrin-inspired iron delivery across the cell membrane using [(L 2 Fe) 2 (μ-O)](L= chlorquinaldol) to harness anticancer activity of ferroptosis

N Abeydeera, K Mudarmah, BD Pant, JA Krause… - Dalton …, 2024 - pubs.rsc.org
Although iron is a bio-essential metal, dysregulated iron acquisition and metabolism result in
production of reactive oxygen species (ROS) due to the Fenton catalytic reaction, which …

Broad-spectrum antimicrobial activity of ultrafine (BiO) 2CO3 NPs functionalized with PVP that can overcome the resistance to ciprofloxacin, AgNPs and meropenem in …

BD Pant, N Abeydeera, R Dubadi, MH Kim, SD Huang - Antibiotics, 2023 - mdpi.com
Although it has no known biochemical role in living organisms, bismuth has been used to
treat syphilis, diarrhea, gastritis and colitis for almost a century due to its nontoxic nature to …

Mechanochemically Synthesized Alumina-Based Mesoporous Materials for Antimicrobial, Adsorption, and Catalytic Applications

R Dubadi - 2023 - search.proquest.com
Porous materials have drawn significant interest due to their unique properties such as high
surface area, enhanced adsorption, biological and catalytic applications. Various methods …