Improved hygiene leading to reduced exposure to microorganisms has been implicated as
one possible cause for the recent “epidemic” of chronic inflammatory diseases (CIDs) in …

Mechanistic studies into the drivers of chronic inflammation in PWH are ongoing and may
aid in tailoring effective therapeutic strategies that can reduce ASCVD risk in this population …

The intestinal epithelial layer serves as a physical and functional barrier between the
microbiota in the lumen and immunologically active submucosa. Th17 T-cell function …

Background Human immunodeficiency virus (HIV) and iron deficiency (ID) affect many
African children. Both HIV and iron status interact with gut microbiota composition and …

Highlights•The human mycobiota contains clinically relevant fungal species.•Longitudinal
sampling provides robust insights into the human mycobiota.•Simultaneous analysis of …

Background Coronavirus disease 2019 (COVID-19) is often associated with mild
thrombocytopenia and increased platelet reactivity. Objective The aim of the current study …

Introduction Perinatally acquired HIV infection (PHIV) occurs during a critical window of
immune development. We investigated changes in systemic inflammation and immune …

Chronic HIV‐infected children suffer from premature aging and aging‐related diseases. Viral
replication induces an ongoing inflammation process, with the release of pathogen …

Background The pathogenesis of rheumatoid arthritis (RA) is believed to initiate at mucosal
sites. The so-called 'mucosal origin hypothesis of RA'postulates an increased intestinal …

Objective: In this study, we aim to investigate the relationship between particulate matter, a
common proxy indicator for air pollution, and markers of inflammation, monocyte activation …