Clathrin-mediated endocytosis is a key process in vesicular trafficking that transports a wide
range of cargo molecules from the cell surface to the interior. Clathrin-mediated endocytosis …

Cryo-electron tomography (cryo-ET) allows 3D volumes to be reconstructed from a set of 2D
projection images of a tilted biological sample. It allows densities to be resolved in 3D that …

Force generation by actin assembly shapes cellular membranes. An experimentally
constrained multiscale model shows that a minimal branched actin network is sufficient to …

Endocytosis and endosomal trafficking are essential processes in cells that control the
dynamics and turnover of plasma membrane proteins, such as receptors, transporters, and …

Clathrin-mediated endocytosis is an essential cellular function in all eukaryotes that is driven
by a self-assembled macromolecular machine of over 50 different proteins in tens to …

Clathrin-mediated endocytosis enables selective uptake of molecules into cells in response
to changing cellular needs. It occurs through assembly of coat components around the …

Actin filaments play multiple roles in the secretory pathway and in endosome dynamics in
mammals, including maintenance of Golgi structure, release of membrane cargo from the …

Clathrin-mediated endocytosis is an essential cellular process that involves the concerted
assembly and disassembly of many different proteins at the plasma membrane. In yeast, live …

Successful sample preparation is the foundation to any structural biology technique.
Membrane proteins are of particular interest as these are important targets for drug design …

Clathrin is best known for its contribution to clathrin-mediated endocytosis yet it also
participates to a diverse range of cellular functions. Key to this is clathrin's ability to …