Coevolution of humans and malaria parasites has generated an intricate balance between
the immune system of the host and virulence factors of the parasite, equilibrating maximal …

Cerebral malaria (CM) is one the major complications occurring during malaria infection.
The mechanisms leading to this syndrome are still not completely understood. Although it is …

Cerebral malaria is a lethal complication of malaria infection characterized by central
nervous system dysfunction and is often not effectively treated by antimalarial combination …

In the murine model of cerebral malaria caused by P. berghei ANKA (PbA), parasite-specific
CD8+ T cells directly induce pathology and have long been hypothesized to kill brain …

Complications from malaria parasite infections still cost the lives of close to half a million
people every year. The most severe is cerebral malaria (CM). Employing murine models of …

The murine model of experimental cerebral malaria (ECM) has been utilised extensively in
recent years to study the pathogenesis of human cerebral malaria (HCM). However, it has …

Canine babesiosis is a tick-borne protozoan disease caused by intraerythrocytic parasites of
the genus Babesia. The infection may lead to anemia in infected dogs. However, anemia is …

Streptococcus suis is an emerging zoonotic pathogen causing severe infections in pigs and
humans. In previous studies, 33 serotypes of S. suis have been identified using serum …

Heme-biosynthetic pathway of malaria parasite is dispensable for asexual stages, but
essential for mosquito and liver stages. Despite having backup mechanisms to acquire …

Plasmodium falciparum malaria is responsible for over 250 million clinical cases every year
worldwide. Severe malaria cases might present with a range of disease syndromes …