Glutamatergic system in depression and its role in neuromodulatory techniques optimization

MAS Khoodoruth, MA Estudillo-Guerra… - Frontiers in …, 2022 - frontiersin.org
Depressive disorders are among the most common psychiatric conditions and contribute to
significant morbidity. Even though the use of antidepressants revolutionized the …

Modulating brain activity and behaviour with tDCS: Rumours of its death have been greatly exaggerated

HL Filmer, JB Mattingley, PE Dux - Cortex, 2020 - Elsevier
Transcranial electrical brain stimulation (tES) techniques have shown substantial promise in
research and applied settings. However, over the last few years the technique has courted …

The effects of left DLPFC tDCS on emotion regulation, biased attention, and emotional reactivity to negative content

PJF Clarke, B Van Bockstaele, W Marinovic… - Cognitive, Affective, & …, 2020 - Springer
The potentiation of neural activity in lateral prefrontal regions via transcranial direct current
stimulation (tDCS) can reduce patterns of biased attention for threat and may facilitate …

The influence of tDCS intensity on decision-making training and transfer outcomes

SE Ehrhardt, HL Filmer, Y Wards… - Journal of …, 2021 - journals.physiology.org
Transcranial direct current stimulation (tDCS) has been shown to improve single-and dual-
task performance in healthy participants and enhance transferable training gains following …

[HTML][HTML] Differences in electric field strength between clinical and non-clinical populations induced by prefrontal tDCS: A cross-diagnostic, individual MRI-based …

Y Mizutani-Tiebel, S Takahashi, T Karali, E Mezger… - NeuroImage: Clinical, 2022 - Elsevier
Introduction Prefrontal cortex (PFC) regions are promising targets for therapeutic
applications of non-invasive brain stimulation, eg transcranial direct current stimulation …

Individual differences in decision strategy relate to neurochemical excitability and cortical thickness

HL Filmer, K Loughnan, JX Seeto, T Ballard… - Journal of …, 2023 - Soc Neuroscience
The speed-accuracy trade-off (SAT), whereby faster decisions increase the likelihood of an
error, reflects a cognitive strategy humans must engage in during the performance of almost …

The efficacy of transcranial direct current stimulation to prefrontal areas is related to underlying cortical morphology

HL Filmer, SE Ehrhardt, TB Shaw, JB Mattingley… - Neuroimage, 2019 - Elsevier
Applying a weak electrical current to the cortex can have effects on a range of behaviours.
Techniques such as transcranial direct current stimulation (tDCS) have been widely used in …

Anodal and cathodal tDCS modulate neural activity and selectively affect GABA and glutamate syntheses in the visual cortex of cats

X Zhao, J Ding, H Pan, S Zhang, D Pan… - The Journal of …, 2020 - Wiley Online Library
Key points The present study showed that anodal and cathodal transcranial direct current
stimulation (tDCS) can respectively increase and decrease the amplitude of visually evoked …

Neural substrates of individual differences in learning generalization via combined brain stimulation and multitasking training

Y Wards, SE Ehrhardt, HL Filmer, JB Mattingley… - Cerebral …, 2023 - academic.oup.com
A pervasive limitation in cognition is reflected by the performance costs we experience when
attempting to undertake two tasks simultaneously. While training can overcome these …

Neurochemical Predictors of Generalized Learning Induced by Brain Stimulation and Training

SE Ehrhardt, Y Wards, R Rideaux… - Journal of …, 2024 - Soc Neuroscience
Methods of cognitive enhancement for humans are most impactful when they generalize
across tasks. However, the extent to which such “transfer” is possible via interventions is …