Marine Aspergillus: A Treasure Trove of Antimicrobial Compounds

H Li, Y Fu, F Song - Marine Drugs, 2023 - mdpi.com
Secondary metabolites from marine organisms are diverse in structure and function. Marine
Aspergillus is an important source of bioactive natural products. We reviewed the structures …

Screening for neuroprotective and rapid antidepressant-like effects of 20 essential oils

KN Tran, NPK Nguyen, LTH Nguyen, HM Shin, IJ Yang - Biomedicines, 2023 - mdpi.com
Depression is a serious psychiatric disorder with high prevalence, and the delayed onset of
antidepressant effects remains a limitation in the treatment of depression. This study aimed …

Opuntia monacantha: Validation of the anti-inflammatory and anti-arthritic activity of its polyphenolic rich extract in silico and in vivo via assessment of pro-and anti …

F Abid, M Saleem, T Jamshaid, U Jamshaid… - Journal of …, 2024 - Elsevier
Ethnopharmacological relevance Opuntia monacantha belongs to the cactus family
Cactaceae and is also known by cochineal prickly pear, Barbary fig or drooping prickly pear …

Alkaloids from Siparuna (Siparunaceae) are predicted as the inhibitors of proteolysis and plasma coagulation caused by snake venom and potentially counteract …

DA Fernandes, BA Gomes, SC Mendonça… - Journal of …, 2024 - Elsevier
Ethnopharmacological relevance Snakebite envenomation (SBE) is the world's most lethal
neglected tropical disease. Bothrops jararaca is the species that causes the greatest number …

Metabolic Profiling and Investigation of the Modulatory Effect of Fagonia cretica L. Aerial Parts on Hepatic CYP3A4 and UGT2B7 Enzymes in Streptozotocin—Induced …

S Kamran, R Anwar, A Noor, MI Ullah, AA Bagalagel… - Antioxidants, 2023 - mdpi.com
Drug-metabolizing enzymes are either boosted or suppressed by diabetes mellitus. This
research was designed to explore Fagonia cretica L. aerial parts' impact on CYP3A4 and …

Virtual Screening and Molecular Docking of Traditional Chinese Medicine Database Reveals Curculigoside as a Promising Inhibitor for Non‐Insulin‐Dependent …

MS Hossain, M Roney, MN Uddin… - …, 2025 - Wiley Online Library
Millions worldwide grapple with diabetes mellitus, a global health burden lacking a definitive
cure. The DrugRep, a web program for multi‐database drug discovery, remains unexplored …

Synthesis and activity of arylcoumarin derivatives with therapeutic effects on diabetic nephropathy

Y Pan, M Zhou, Z Liu, C Hao, J Zhai, R Liu… - Archiv der …, 2024 - Wiley Online Library
In the literature, daidzein has been reported to exhibit cardiovascular protective effects and
hypoglycemic activity in mice. We sought to design and synthesize a novel compound, SJ‐6 …

Predicting the Anti-SARS-CoV-2 Potential of Isoquinoline Alkaloids from Brazilian Siparunaceae Species Using Chemometric Tools

BA Gomes, DA Fernandes, SC Mendonça… - International Journal of …, 2025 - mdpi.com
The COVID-19 pandemic has caused over 7 million deaths globally in the past four years.
Siparuna spp.(Siparunaceae), which is used in Brazilian folk medicine, is considered a …