Type 2 diabetes mellitus (T2DM) and sarcopenia (low skeletal muscle mass and function)
share a bidirectional relationship. The prevalence of these diseases increases with age and …

Metabolic and structural changes in skeletal muscle that accompany obesity are often
associated with the development of insulin resistance. The first events in the pathogenesis of …

Background. An excessive amount of adipose tissue may contribute to sarcopenia and may
be one mechanism underlying accelerated loss of muscle mass and strength with aging. We …

The prevalence of chronic diseases has risen along with increased longevity. Co-
occurrence of two or more chronic diseases in an individual (multimorbidity) is prevalent and …

Introduction Although decline in muscle mass and quality and resulting declines in muscle
strength are associated with aging, more research is needed in general populations to …

Epidemiological studies show that obesity has deleterious effects on the brain and cognitive
function in the elderly population. However, the specific mechanisms through which aging …

Objectives To examine long‐term changes in handgrip strength and the factors predicting
handgrip strength decline. Design Longitudinal cohort study with 22 years of follow‐up …

There is increasing evidence that vascular risk factors, including aging, hypertension,
diabetes mellitus, and obesity, promote cognitive impairment; however, the underlying …

Background: few studies have examined associations of multi-faceted demographic, health
and lifestyle factors with long-term change in grip strength performance across the adult …

Objective Το investigate associations between adherence to the Mediterranean diet and
frailty in a Greek population of older adults. Design Cross-sectional study. Setting Data were …