Distinct clinical and prognostic features of myelodysplastic syndrome in patients from the Middle East, North Africa, and beyond: A systemic review

A Al-Haidose, MA Yassin, MN Ahmed… - Journal of Clinical …, 2023 - mdpi.com
Myelodysplastic syndrome (MDS) describes a group of bone marrow malignancies with
variable morphologies and heterogeneous clinical features. The aim of this study was to …

Comprehensive analysis of genetic factors predicting overall survival in Myelodysplastic syndromes

N Maurya, P Mohanty, S Dhangar, P Panchal… - Scientific Reports, 2022 - nature.com
Myelodysplastic syndromes (MDS) are a group of clonal hematological disease with high
risk of progression to AML. Accurate risk stratification is of importance for the proper …

Alterations of the expression of TET2 and DNA 5-hmC predict poor prognosis in Myelodysplastic Neoplasms

AA Seethy, K Pethusamy, T Kushwaha, G Kumar… - BMC cancer, 2023 - Springer
Abstract Background Myelodysplastic Neoplasms (MDS) are clonal stem cell disorders
characterized by ineffective hematopoiesis and progression to acute myeloid leukemia …

Secretion and expression of matrix metalloproteinase-2 and 9 from bone marrow mononuclear cells in myelodysplastic syndrome and acute myeloid leukemia

AK Chaudhary, S Chaudhary, K Ghosh… - Asian Pacific Journal …, 2016 - journal.waocp.org
Background: Matrix metalloproteinase-2 (gelatinase-A, Mr 72,000 type IV collagenase, MMP-
2) and-9 (gelatinase-B, Mr 92,000 type IV collagenase, MMP-9) are key molecules that play …

Chromosomal abnormalities in primary myelodysplastic syndrome

A Rashid, M Khurshid, U Shaikh… - JCPSP: Journal of the …, 2014 - ecommons.aku.edu
Objective: To determine the frequency of cytogenetic abnormalities in patients diagnosed as
primary myelodysplastic syndrome (MDS) using conventional karyotyping. Study Design …

Higher prevalence of poor prognostic markers at a younger age in adult patients with myelodysplastic syndrome–evaluation of a large cohort in India

VM Srivastava, SC Nair, M Joy, MT Manipadam… - Molecular …, 2024 - Springer
Background The karyotype is a major determinant of prognosis in myelodysplastic syndrome
(MDS). Details of the cytogenetic profile of MDS in South Asia are limited because …

Clinical, hematological, and cytogenetic profile of adult myelodysplastic syndrome in a tertiary care center

S Narayanan - Journal of Blood Medicine, 2017 - Taylor & Francis
Background Myelodysplastic syndrome (MDS), a disorder of clonal hematopoiesis, is an
important clinical entity, but most of the studies available are conducted among the Western …

[HTML][HTML] Cytogenetic features in primary myelodysplastic syndrome Egyptian patients

Y Elnahass, L Youssif - Journal of Advanced Research, 2018 - Elsevier
Karyotype is the most important diagnostic and prognostic parameter in myelodysplastic
syndromes (MDS) and is abnormal in approximately 50% of patients. We emphasized the …

Phenotypic and Cytogenetic Characterization of Mesenchymal Stromal Cells in De Novo Myelodysplastic Syndromes

A Rathnayake, HWW Goonasekera… - Analytical cellular …, 2016 - Wiley Online Library
Bone marrow (BM) mesenchymal stem/stromal cells (MSCs) are vital in hematopoiesis.
Whether BM‐MSCs alter their characteristics in Myelodysplastic Syndromes (MDS) is still …

[PDF][PDF] Myelodysplastic syndrome in Pakistan: Clinicohematological characteristics, cytogenetic profile, and risk stratification

R Mahmood, C Altaf, P Ahmed… - Turkish Journal of …, 2018 - jag.journalagent.com
Objective: Myelodysplastic syndrome (MDS) is a group of bone marrow diseases that not
only have variable morphological presentation and heterogeneous clinical courses but also …