Over the last few years, several advances have been made toward the development and
production of in vitro human skin models for the analysis and testing of cosmetic and …

Endothelial cells throughout the body are heterogeneous, and this is tightly linked to the
specific functions of organs and tissues. Heterogeneity is already determined from …

In this paper, we review and analyze the commonly available wound healing models
reported in the literature and discuss their advantages and issues, considering their …

Despite the advancements in skin bioengineering, 3D skin constructs are still produced as
flat tissues with open edges, disregarding the fully enclosed geometry of human skin …

As the largest organ of the human body, the skin has a complex multi-layered structure. The
composition of the skin includes cells, extracellular matrix (ECM), vascular networks, and …

This comprehensive review explores the multifaceted landscape of skin bioprinting,
revolutionizing dermatological research. The applications of skin bioprinting utilizing …

In vitro engineered skin models are emerging as an alternative platform to reduce and
replace animal testing in dermatological research. Despite the progress made in recent …

The process of angiogenesis plays a pivotal role in skin regeneration, ensuring the provision
of nutrients and oxygen to the nascent tissue, thanks to the formation of novel microvascular …

Significance: Nonhealing wounds are a significant burden for the health care system all over
the world. Existing treatment options are not enough to promote healing, highlighting the …

Inadequate vasculature poses a significant challenge in the clinical translation of tissue
engineering constructs. Current strategies for vascularization typically recruit short-lived …